Prediction of ischaemic and haemorrhagic stroke by self-measured blood pressure at home: the Ohasama study
Prediction of ischaemic and haemorrhagic stroke by self-measured blood pressure at home: the Ohasama study
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DOI：
10.1097/00126097-200412000-00009
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发表时间：
2004-12-01
影响因子：
1.3
通讯作者：
Imai, Y
中科院分区：
文献类型：
--
作者：
Ohkubo, T;Asayama, K;Imai, Y
目的探讨家庭自测血压（家庭血压）对脑卒中风险及脑卒中亚型的预测价值。方法：研究人员对日本普通人群中年龄为40岁、无中风史的1702人进行了家庭血压测量，并在平均10.6年之后继续进行随访。采用Cox比例风险回归模型检验血压对卒中风险的预后意义，并对可能的混杂因素进行调整。结果家庭血压与脑卒中风险及亚型呈线性相关。平均而言，家庭收缩压/舒张压每升高10/5 mmHg，总卒中风险分别增加约30% /20%。出血性卒中（脑内和蛛网膜下腔出血）的风险与缺血性卒中（脑梗死和短暂性缺血发作（TIA））的风险也存在类似的关系。与常规血压值相比，中风和亚型的风险与家庭血压值的关系明显更大。这是第一个证明家庭血压是普通人群出血性和缺血性中风的独立预测因子的研究。(C) 2004利平科特·威廉姆斯·威尔金斯。
Objective To examine the predictive value of self-measured blood pressure values taken at home (home blood pressure) for risk of stroke and subtypes.Methods We obtained home blood pressure measurements from 1702 people, aged : 40 years, without a history of stroke, in the general population in Japan, and continued follow-up after a mean period of 10.6 years. The prognostic significance of blood pressure for stroke risk was examined using the Cox proportional hazards regression model, which was adjusted for possible confounding factors.Results There was a linear relationship between home blood pressure and risk of stroke and subtypes. On average, each 10/5 mmHg elevation in home systolic/diastolic blood pressure respectively, was associated with an approximately 30/20% respectively, higher risk of total stroke. A similar relationship was observed for the risk of haemorrhagic stroke (intracerebral and subarachnoid haemorrhage), and the risk of ischaemic stroke [cerebral infarction and transient ischaemic attack (TIA)]. The risk of stroke and subtypes showed a significantly greater relation with home blood pressure values compared to conventional blood pressure values.Conclusions This is the first study to demonstrate that home blood pressure is an independent predictor for haemorrhagic and ischaemic stroke, in the general population. (C)) 2004 Lippincott Williams Wilkins.