Relative Atrial Natriuretic Peptide Deficiency and Inadequate Renin and Angiotensin II Suppression in Obese Hypertensive Men
Relative Atrial Natriuretic Peptide Deficiency and Inadequate Renin and Angiotensin II Suppression in Obese Hypertensive Men
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DOI：
10.1161/hypertensionaha.111.00791
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发表时间：
2013-07-01
期刊：
影响因子：
8.3
通讯作者：
Jeppesen, Jorgen L.
中科院分区：
文献类型：
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作者：
Asferg, Camilla L.;Nielsen, Soren J.;Jeppesen, Jorgen L.
肥胖是高血压的强烈危险因素，但肥胖导致高血压的机制尚不完全清楚。在此背景下，我们评估了63名肥胖高血压男性(肥胖：体重指数，30.0 kg/m(2)；24小时动态血压，130/80 mm Hg)的膳食钠摄入量、血清利钠肽(NPs)水平和肾素-血管紧张素系统的活性；40名正常血压肥胖男性(肥胖：体重指数，30.0 kg/m(2)；24小时动态血压，
Obesity is a strong risk factor for hypertension, but the mechanisms by which obesity leads to hypertension are incompletely understood. On this background, we assessed dietary sodium intake, serum levels of natriuretic peptides (NPs), and the activity of the renin-angiotensin system in 63 obese hypertensive men (obeseHT: body mass index, 30.0 kg/m(2); 24-hour ambulatory blood pressure, 130/80 mm Hg), in 40 obese normotensive men (obeseNT: body mass index, 30.0 kg/m(2); 24-hour ambulatory blood pressure,