Vitamin A intake and infection are associated with plasma retinol among pre-school children in rural Zambia
Vitamin A intake and infection are associated with plasma retinol among pre-school children in rural Zambia
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DOI：
10.1017/s1368980012000924
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发表时间：
2012-09-01
影响因子：
3.2
通讯作者：
Kafwembe, Emmanuel
中科院分区：
文献类型：
--
作者：
Hotz, Christine;Chileshe, Justin;Kafwembe, Emmanuel
目的：为了确定赞比亚儿童维生素A缺乏症、感染和维生素A摄入充足性的患病率，以及膳食维生素A和感染对维生素A状态的影响。设计：通过24小时回忆法对维生素A摄入量进行横断面调查，通过血浆视黄醇和改良的相对剂量反应试验对维生素A状态进行调查，并通过急性期蛋白质进行感染。农村社区在中部和东部省份的Zambia.Subjects：儿童2-5 years age.Results：维生素A缺乏症的患病率是56%的血浆视黄醇，48%的感染调整血浆视黄醇和22%的修改后的相对剂量反应试验。大多数儿童（61%）目前有感染。维生素A摄入量相对较高（在收获/收获后早期和收获后后期，维生素A摄入量分别为331至585 μ g视黄醇活性当量/d），
Objective: To determine the prevalence of vitamin A deficiency, infection and adequacy of vitamin A intakes among Zambian children, and the contribution of dietary vitamin A and infection to vitamin A status.Design: A cross-sectional survey of vitamin A intakes by the 24 h recall method, vitamin A status by plasma retinol and the modified relative dose-response test, and infection by acute-phase proteins.Setting: Rural communities in Central and Eastern Provinces of Zambia.Subjects: Children 2-5 years of age.Results: The prevalence of vitamin A deficiency was 56% by plasma retinol, 48% with infection-adjusted plasma retinol and 22% by the modified relative dose-response test. The majority of children (61%) had a current infection. Vitamin A intakes were relatively high (331 to 585 mu g retinol activity equivalents/d in the harvest/early post-harvest and late post-harvest seasons, respectively) and the prevalence of inadequate intakes was