Complexation and coacervation of polyelectrolytes with oppositely charged colloids
Complexation and coacervation of polyelectrolytes with oppositely charged colloids
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DOI：
10.1016/j.cis.2011.06.006
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发表时间：
2011-09-14
影响因子：
15.6
通讯作者：
Dubin, Paul L.
中科院分区：
文献类型：
--
作者：
Kizilay, Ebru;Kayitmazer, A. Basak;Dubin, Paul L.
聚电解质-胶体凝聚可以被视为复合凝聚的一个子类别，但其独特之处在于（1）保留了胶体的结构和性质，以及（2）降低了聚电解质-胶体（PE-PE）系统的异质性和构型复杂性。对蛋白质-胶束凝聚体的兴趣来自于生物功能的保存;此外，胶束的几何和电荷各向同性允许与理论进行更好的比较，考虑到胶体电荷密度的核心作用。在这两个系统的上下文中，我们描述的关键条件，复杂的形成和凝聚方面的胶体和dielectric电荷密度，离子强度，PE分子量（MW），和化学计量;和温度和剪切的影响，这是独特的PE胶束系统。凝聚过程中讨论的理论治疗和模型，实验结果的支持。我们指出如何可溶性聚集体，受到各种平衡和approxionation的影响，可以自组装导致在宏观上均匀的凝聚层的异质性，在多个长度尺度。由爱思唯尔公司出版
Polyelectrolyte-colloid coacervation could be viewed as a sub-category of complex coacervation, but is unique in (1) retaining the structure and properties of the colloid, and (2) reducing the heterogeneity and configurational complexity of polyelectrolyte-polyelectrolyte (PE-PE) systems. Interest in protein-polyelectrolyte coacervates arises from preservation of biofunctionality; in addition, the geometric and charge isotropy of micelles allows for better comparison with theory, taking into account the central role of colloid charge density. In the context of these two systems, we describe critical conditions for complex formation and for coacervation with regard to colloid and polyelectrolyte charge densities, ionic strength, PE molecular weight (MW), and stoichiometry; and effects of temperature and shear, which are unique to the PE-micelle systems. The coacervation process is discussed in terms of theoretical treatments and models, as supported by experimental findings. We point out how soluble aggregates, subject to various equilibria and disproportionation effects, can self-assemble leading to heterogeneity in macroscopically homogeneous coacervates, on multiple length scales. Published by Elsevier B.V.