WAIST CIRCUMFERENCE AND ABDOMINAL SAGITTAL DIAMETER - BEST SIMPLE ANTHROPOMETRIC INDEXES OF ABDOMINAL VISCERAL ADIPOSE-TISSUE ACCUMULATION AND RELATED CARDIOVASCULAR RISK IN MEN AND WOMEN

WAIST CIRCUMFERENCE AND ABDOMINAL SAGITTAL DIAMETER - BEST SIMPLE ANTHROPOMETRIC INDEXES OF ABDOMINAL VISCERAL ADIPOSE-TISSUE ACCUMULATION AND RELATED CARDIOVASCULAR RISK IN MEN AND WOMEN
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DOI:
10.1016/0002-9149(94)90676-9
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发表时间:
1994-03-01
影响因子:
2.8
通讯作者:
LUPIEN, PJ
LUPIEN, PJ
中科院分区:
医学3区
文献类型:
--
作者:
POULIOT, MC;DESPRES, JP;LUPIEN, PJ

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通过计算机断层扫描测量腹部内脏脂肪组织的数量是与腹部肥胖相关的潜在“动脉粥样硬化”代谢紊乱的关键相关因素。在这项对81名男性和70名女性样本进行的研究中,提供了腹部内脏脂肪组织积累和相关心血管疾病危险因素(甘油三酯和高密度脂蛋白胆固醇水平、空腹和葡萄糖后胰岛素和葡萄糖水平)的人体测量相关数据。结果表明,与常用的腰臀比(WHR)相比,腰围和腹矢状直径与腹部内脏脂肪组织积累的相关性更好。在女性中,腰围和腹矢状直径与代谢变量的关系也比腰重比密切。当样本被分成腰围、腰宽比或腹矢状直径的五分位数时,值得注意的是,腰围和腹矢状直径的增加与空腹和葡萄糖后胰岛素水平的增加更为一致,而不是腰宽比的增加,尤其是在女性中。这些结果表明,腰围或腹矢状直径,而不是腰宽比,应该作为腹部内脏脂肪组织沉积和心血管风险评估的指标。从这些数据可以看出,腰围值超过约100厘米,或腹矢状直径值bbb25厘米,最有可能与潜在的“致动脉粥样硬化”代谢紊乱有关。
The amount of abdominal visceral adipose tissue measured by computed tomography is a critical correlate of the potentially ''atherogenic'' metabolic disturbances associated with abdominal obesity. In this study conducted in samples of 81 men and 70 women, data are presented on the anthropometric correlates of abdominal visceral adipose tissue accumulation and related cardiovascular disease risk factors (triglyceride and high-density lipoprotein cholesterol levels, fasting and postglucose insulin and glucose levels). Results indicate that the waist circumference and the abdominal sagittal diameter are better correlates of abdominal visceral adipose tissue accumulation than the commonly used waist-to-hip ratio (WHR). In women, the waist circumference and the abdominal sagittal diameter also appeared more closely related to the metabolic variables than the WHR. When the samples were divided into quintiles of waist circumference, WHR or abdominal sagittal diameter, it was noted that increasing values of waist circumference and abdominal sagittal diameter were more consistently associated with increases in fasting and postglucose insulin levels than increasing values of WHR, especially in women. These findings suggest that the waist circumference or the abdominal sagittal diameter, rather than the WHR, should be used as indexes of abdominal visceral adipose tissue deposition and in the assessment of cardiovascular risk. It is suggested from these data that waist circumference values above approximately 100 cm, or abdominal sagittal diameter values >25 cm are most likely to be associated with potentially ''atherogenic'' metabolic disturbances.