Decreased susceptibility to ciprofloxacin in Salmonella enterica serotype Typhi, United Kingdom

Decreased susceptibility to ciprofloxacin in Salmonella enterica serotype Typhi, United Kingdom
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DOI:
10.3201/eid0703.017315
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发表时间:
2001-05-01
影响因子:
11.8
通讯作者:
Ward, LR
Ward, LR
中科院分区:
医学2区
文献类型:
--
作者:
Threlfall, EJ;Ward, LR

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1999年,23%的英国伤寒沙门氏菌血清型分离株对环丙沙星(MIC 0.25-1.0 mg/L)的敏感性降低;超过一半的分离株对氯霉素、氨苄青霉素和甲氧苄啶也有耐药性。人们注意到,治疗失败的情况越来越多。大多数感染发生在最近有印度和巴基斯坦旅行史的患者中。
In 1999, 23% of Salmonella enterica serotype Typhi isolates from patients in the United Kingdom exhibited decreased susceptibility to ciprofloxacin (MIC 0.25-1.0 mg/L); more than half were also resistant to chloramphenicol, ampicillin, and trimethoprim. Increasing numbers of treatment failures have been noted. Most infections have been in patients with a recent history of travel to India and Pakistan.