Epidemiology and morbidity of Schistosoma mansoni infection in a fishing community along Lake Albert in Uganda
Epidemiology and morbidity of Schistosoma mansoni infection in a fishing community along Lake Albert in Uganda
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DOI：
10.1016/j.trstmh.2004.06.003
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发表时间：
2004-12-01
影响因子：
2.2
通讯作者：
Vennervald, BJ
中科院分区：
文献类型：
--
作者：
Kabatereine, NB;Kemijumbi, J;Vennervald, BJ
1996年11月至1997年1月，在乌干达阿尔伯特湖沿岸布蒂亚巴的皮伊达渔场，研究了曼氏血吸虫的感染、相关发病率和症状。研究表明，曼氏血吸虫是高度流行的，总流行率为72%，平均密度为每克粪便419.4个卵子(仅对阳性)，37.8%的配偶和33.0%的雌性粪便排泄超过1000EPG。患病率和强度在10-14岁年龄组达到高峰，并随着年龄的增长而下降。雌性受感染的程度比配偶轻。部落之间的差异也表现出来。据报道，腹泻和腹痛在皮伊达很常见。然而，曼氏血吸虫的感染强度与这些情况之间没有明显的相关性，这表明关于曼氏血吸虫相关症状的回溯性问卷的价值有限。根据超声检查，器官肿大是常见的，肝肿大与重度曼氏沙门氏菌感染有关。未发现脾肿大与感染之间的相关性。这项研究强调，曼氏血吸虫病是皮伊达渔区的一个主要公共卫生问题，可能在许多类似的渔区也是如此。这些观察结果要求立即进行干预，并有助于规划可持续发病率控制的长期战略。(C)2004年皇家热带医学和卫生学会。爱思唯尔有限公司出版。保留所有权利。
Schistosoma mansoni infection, associated morbidity and symptoms were studied in Piida fishing community at Butiaba, along Lake Albert, Uganda, from November 1996 to January 1997. The study revealed that S. mansoni is highly endemic with an overall prevalence of 72%, a mean intensity of 419.4 eggs per gram (epg) faeces (geometric mean for positives only), with 37.8% of mates and 33.0% of females excreting over 1000 epg. Prevalence and intensity peaked in the 10-14 year old age group and decreased with increasing age. Females were less heavily infected than mates. Differences were also shown between tribes. Diarrhoea and abdominal pain were commonly reported in Piida. However, no clear-cut correlation between intensity of S. mansoni infection and these conditions could be demonstrated, indicating that retrospective questionnaires concerning S. mansoni related-symptomatology are of limited value. Organomegaly, as assessed by ultrasonography, was frequent and hepatomegaly was associated with heavy S. mansoni infection. No correlation was demonstrated between splenomegaly and infection. This study emphasizes that schistosomiasis mansoni is a major public health problem in Piida fishing community and presumably also in many similar fishing communities. These observations call for immediate intervention and can help in planning tong-term strategies for sustainable morbidity control. (C) 2004 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.