The optimal setting of complex fractionated atrial electrogram software in substrate ablation for atrial fibrillation

The optimal setting of complex fractionated atrial electrogram software in substrate ablation for atrial fibrillation
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复杂分割心房电图软件在心房颤动基质消融中的最佳设置

DOI:
10.1016/j.joa.2014.04.006
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发表时间:
2015
影响因子:
2
通讯作者:
T. Hashiguchi
T. Hashiguchi
中科院分区:
--
文献类型:
--
作者:
Fuminori Namino;Yasuhisa Iriki;Ryuichi Maenosono;H. Ichiki;Hideki Okui;Akino Yoshimura;N. Oketani;Masakaze Matsushita;M. Ohishi;T. Hashiguchi

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背景复杂碎裂心房电图(CFAE)靶向导管消融(CFAE消融)需要高的房颤(AF)终止率才能提供良好的结局。我们确定了最佳设置的CFAE software.MethodsIn我们的430例连续患者,房颤终止97(234/242)和79%(149/188)的阵发性和持续性房颤的患者,分别由CFAE消融结合(31%)或不(69%)肺静脉隔离,偶尔与尼非卡兰输注。我们分析了109例接受CFAE消融的连续患者,以确定通过CARTO 3上的CFAE软件比较主观与客观决策的最佳设置。我们比较了三种设置:默认设置(0.05-0.15 mV,50-120 ms)和两个修改设置(#1:0.05-0.30 mV,40-70 ms,#2:0.05-0.13 mV,10-20 ms)。我们回顾性分析了消融前左心房标测期间的11,425个点和10,306个被主观检测并消融为CFAE点的点。结果在默认设置下,准确性、敏感性、特异性、阳性生产值和阴性生产值分别为67%、42%、77%、48%和73%。使用改良设置#1,数值分别为78、55、87、74和77%,而改良设置#2分别为64、82、60、53和91%。结论这些数据表明,设置#1通常上级默认设置,而设置#2对于排除不需要消融的区域是最佳的。最佳的CFAE软件设置为0.05-0.30 mV的电压和40-70 ms的间隔参数。
BackgroundComplex fractionated atrial electrogram (CFAE)-targeted catheter ablation (CFAE ablation) requires a high rate of atrial fibrillation (AF) termination to provide good outcomes. We determined the optimal settings of CFAE software.MethodsIn our 430 consecutive patients, AF was terminated in 97 (234/242) and 79% (149/188) of patients with paroxysmal and persistent AF, respectively, by CFAE ablation combined with (31%) or without (69%) pulmonary vein isolation, occasionally with nifekalant infusion. We analyzed 109 consecutive patients who underwent CFAE ablation to determine the optimal settings for comparing subjective versus objective decisions by the CFAE software on CARTO3. We compared three settings: the default setting (0.05–0.15 mV, 50–120 ms) and two modified settings (#1: 0.05–0.30 mV, 40–70 ms, #2: 0.05–0.13 mV, 10–20 ms). We retrospectively analyzed 11,425 points during left atrial mapping before ablation and 10,306 points that were subjectively detected and ablated as CFAE points. An interval confidence level ≥6 denoted a site with CFAE.ResultsWith the default setting, the accuracy, sensitivity, specificity, positive productive value, and negative productive values were 67, 42, 77, 48, and 73%, respectively. With modified setting #1, the values were 78, 55, 87, 74, and 77%, respectively, versus 64, 82, 60, 53, and 91%, respectively, for modified setting #2.ConclusionThese data suggest that setting #1 was generally superior to the default setting, whereas setting #2 was optimal for excluding areas not requiring ablation. The optimal CFAE software setting was a voltage of 0.05–0.30 mV and an interval parameter of 40–70 ms.
左心房顶线性阻滞对心房颤动的疗效。
DOI: --
发表时间: 2010
期刊: J.Cardiol. 55
影响因子: --
作者:
Senga M;Fujii E;Sugiura S;Yamazato S;Sugiura E;Nakamura M;Miyahara M;Ito M.
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发表时间: 2019
期刊:
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作者:
Mariya T;Kato T;Sugimoto T;Miyai S;Inagaki H;Ohye T;Sugihara E;Muramatsu Y;Mizuno S;Kurahashi H.;Hitoshi Ichiki
通讯作者: Hitoshi Ichiki
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DOI: --
发表时间: 2011
期刊:
影响因子: --
作者:
Nakazawa Y;Ito M;et al
通讯作者: et al