Varying 10-methacryloyloxydecyl dihydrogen phosphate (10-MDP) level improves polymerisation kinetics and flexural strength in self-adhesive, remineralising composites
Varying 10-methacryloyloxydecyl dihydrogen phosphate (10-MDP) level improves polymerisation kinetics and flexural strength in self-adhesive, remineralising composites
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DOI：
10.1016/j.dental.2021.06.006
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发表时间：
2021-08-12
期刊：
影响因子：
5
通讯作者：
Young, Anne M.
中科院分区：
文献类型：
--
作者：
Delgado, Antonio H. S.;Owji, Nazanin;Young, Anne M.
目标.为了评估系统地改变浓度的10-甲基丙烯酰氧基癸基磷酸二氢酯（10-MDP）与3%4-Meta对聚合动力学和收缩率、双轴弯曲强度（BFS）和模量的影响，对复合材料进行了交联。通过将聚（丙二醇）二甲基丙烯酸酯（24wt%）、邻苯二酚（1wt%）和MDP（0%、5%、10%、15%和20wt%）或4-Meta（3%）添加到氨基甲酸酯二甲基丙烯酸酯中来制备复合材料。将这些与含有8重量%磷酸一钙和4重量%聚赖氨酸的玻璃填料混合（粉末-液体比为3：1）。在20秒光暴露（37 ° C）后，用ATR-FTIR评估连续光谱变化以监测聚合动力学（n = 3）。采用最终外推转化率（D-C，D-max）来计算聚合收缩率。使用球-环夹具装置测定干燥储存24小时的圆盘试样（10 x 1 mm; n = 10）的BFS和模量。当MDP从0增加到20wt%时，最大聚合速率和D-C、D-max分别从2.5线性增加到3.5%s（-1）和67线性增加到83%。含3% 4-Meta的值分别为2.6% s（-1）和78%。所有制剂的收缩率为3.8 +/-0.3%。将4-Meta或MDP分别从0%提高到3%与5%相比，将强度从106 MPa提高到145 MPa与136 MPa。观察到随着MDP浓度升高呈下降趋势。弹性模量随MDP的增加没有表现出特定的趋势。虽然最终转化水平通过3%4-Meta或> 5%MDP提高，但趋势与强度无关。因此，具有3%4-Meta或5%MDP的峰强度可能是由于酸性单体在亲水性、非硅烷处理的颗粒和聚合物基质之间提供连接。(C)2021年牙科材料学院。爱思唯尔公司出版All rights reserved.
Objectives. To assess the influence of systematically varying concentrations of 10-methacryloyloxydecyl dihydrogen phosphate (10-MDP) versus 3% 4-META on the polymerisation kinetics and shrinkage, biaxial flexural strength (BFS) and modulus of remineralising composites.Methods. Composites were prepared by adding poly(propylene glycol) dimethacrylate (24 wt%), camphorquinone (1 wt%) and MDP (0%, 5%, 10%, 15% and 20 wt%) or 4-META (3%) to urethane dimethacrylate. These were mixed with glass fillers containing 8 wt% mono- calcium phosphate and 4 wt% polylysine (powder-liquid ratio of 3:1). Continuous spectral changes, following 20 s light exposure (37 degrees C), were assessed with an ATR-FTIR to monitor polymerisation kinetics (n = 3). Final extrapolated conversions (D-C,D-max) were employed to calculate polymerisation shrinkage. BFS and modulus of 24-h dry stored disc specimens (10 x 1 mm; n = 10) were determined using a ball-on-ring jig setup.Results. Maximum rate of polymerisation and D-C,D-max increased linearly from 2.5 to 3.5% s(-1) and 67 to 83%, respectively, upon increasing MDP from 0 to 20 wt%. Values with 3% 4-META were 2.6% s(-1) and 78%. Shrinkage was 3.8 +/- 0.3% for all formulations. Raising 4-META or MDP from 0 to 3 versus 5%, respectively, increased strength from 106 to 145 versus 136 MPa. A decreasing trend with higher MDP concentrations was noted. Elastic modulus showed no specific trend upon MDP increase.Significance. Whilst final conversion levels were enhanced by 3% 4-META or >5% MDP, trends did not correlate with strength. Peak strengths with 3% 4-META or 5% MDP may therefore be due to acidic monomers providing linkage between the hydrophilic, non-silane treated particles and the polymer matrix. (C) 2021 The Academy of Dental Materials. Published by Elsevier Inc. All rights reserved.