Some issues in facial transplantation

Some issues in facial transplantation
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面部移植中的一些问题

DOI:
10.1111/j.1600-6143.2008.02352.x
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发表时间:
2008-10-01
影响因子:
8.8
通讯作者:
Shuzhong, G.
Shuzhong, G.
中科院分区:
医学2区
文献类型:
--
作者:
Chenggang, Y.;Yan, H.;Shuzhong, G.

文献摘要

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人类面部移植是同种异体复合组织移植的一种形式,现已成为临床现实。2006年4月,我们进行了世界上第二例面部部分移植手术。我们回顾了与面部移植相关的一些问题,特别是在我科接受面部移植的个体。我们讨论了面部移植的手术适应症、技术、风险与收益、知情同意以及心理、社会和财务问题。我们认为,随着同种异体复合组织移植的进展,面部部分或全部移植正成为治疗严重毁容患者的一种及时有效的治疗方法。然而,还有很多问题没有解决,而且我们只在三个人身上进行了移植,没有长期结果数据可用。面部移植需要进一步的研究。
Human facial transplantation, a form of composite tissue allotransplantation, has now become a clinical reality. We carried out the world's second partial facial transplantation in April 2006. We reviewed some issues associated with facial transplantation, especially focusing on the individual who underwent the transplant in our department. We discussed surgical indications, techniques, risks versus benefits, informed consent and psychosocial, societal and financial issues of facial transplantation. In our opinion, with the progresses in composite tissue allotransplantation, partial or full facial transplantation is becoming a timely and effective remedy for the significantly disfigured patients. However, there are a lot of problems unsolved, and as we have performed the transplant on only three individuals, no long-term outcome data are available. Facial transplantation needs further research.