Long-term retention of a conditioned taste aversion in preweanling and adult rats

Long-term retention of a conditioned taste aversion in preweanling and adult rats
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断奶前和成年大鼠条件性味觉厌恶的长期保留

DOI:
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发表时间:
1980
期刊:
影响因子:
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通讯作者:
N. Spear
N. Spear
中科院分区:
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文献类型:
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作者:
P. A. Steinert;R. Infurna;N. Spear

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在断奶前(18 日龄)和成年大鼠中研究了短(6 天)或长(60 天)间隔后条件性味觉厌恶的保留和消失。采用仅味觉和仅疾病控制条件,以及 US 浓度的变化(保持 LiCl 量恒定)。结果表明,在短暂的保留间隔后,两个年龄段的味觉厌恶保留程度是相同的。然而,经过长时间的间隔后,18 天大的老鼠表现出比成年老鼠明显更弱的味觉厌恶——婴儿失忆症。控制美国浓度对年龄或保留间隔的味觉厌恶程度没有影响。讨论了这些结果对婴儿失忆症和一般学习规律的影响。
The retention and extinction of a conditioned taste aversion after either short (6-day) or long (60-day) intervals was investigated in preweanling (18-day-old) and adult rats. Taste-only and illness-only control conditions were employed, as were variations in the concentration of the US (holding LiCl amount constant). Results indicated that after the short retention interval, retention of the taste aversion was equivalent for both ages. After the long interval, however, the 18-day-old rats exhibited significantly weaker taste aversion than their adult counterparts— infantile amnesia. Manipulation of US concentration had no effect on the magnitude of the taste aversions for either age or retention interval. The results are discussed in terms of their implications for infantile amnesia and general laws of learning.