A new MRI approach for accurately implanting microelectrodes into deep brain structures of the rhesus monkey (Macaca mulatta)
A new MRI approach for accurately implanting microelectrodes into deep brain structures of the rhesus monkey (Macaca mulatta)
复制标题
一种新的 MRI 方法可将微电极准确植入恒河猴（Macaca mulatta）的大脑深部结构
DOI：
10.1016/j.jneumeth.2010.07.039
复制
发表时间：
2010-11-30
影响因子：
3
通讯作者：
Hu Xintian
中科院分区：
文献类型：
--
作者：
Wu Jing;Wang Wenchao;Hu Xintian
微电极的准确植入是许多神经生理学家面临的一个重大难题。本文报道了一种新的方法，通过磁共振成像（MRI）来促进电极植入的精确定位，使相关的大脑结构和MRI可见的外部标记锚定在颅骨上（在本例中为内径为0.5 mm的刚性玻璃管）可以显示，通过参考这些标记来显示大脑目标的坐标利用这种新方法，记录电极成功地植入了恒河猴的上丘（SC），并出现了误差
The accurate implantation of microelectrodes is a significant difficulty facing many neurophysiologists This paper reports on a new method used to promote the precise positioning of electrode implantation through magnetic resonance imaging (MRI) allowing both the relevant brain structure and the MRI-visible external markers anchored on the skull (In this case rigid glass tubes with a 0 5 mm Internal diameter) to be displayed By referencing these markers the coordinates of the brain target were calculated Using this novel approach recording electrodes were successfully Implanted Into the superior colliculus (SC) of rhesus monkeys with an error