Displacement of the Retina and Its Recovery After Vitrectomy in Idiopathic Epiretinal Membrane
Displacement of the Retina and Its Recovery After Vitrectomy in Idiopathic Epiretinal Membrane
复制标题
DOI：
10.1016/j.ajo.2013.01.021
复制
发表时间：
2013-06-01
影响因子：
4.2
通讯作者：
Fujiwara, Atsushi
中科院分区：
文献类型：
--
作者：
Nitta, Eri;Shiraga, Fumio;Fujiwara, Atsushi
目的：研究特发性视网膜前膜（ERM）玻璃体切除术后视网膜移位及其变化。设计：前瞻性、干预性病例系列。方法：连续53例56只眼的ERM患者行玻璃体切除术，摘除ERM并内限制膜剥离。在玻璃体切除术前、术后1、3、6、12个月检查眼底自动荧光（FAF）成像。主要观察指标为FAF显像检测ERM视网膜移位的眼占比及玻璃体切除术后视网膜移位的恢复率。结果：手术前，56只眼中有37只（66.1%）的FAF摄影显示血管拱廊内有超自体荧光线。这些线条似乎与视网膜血管移位前的位置一致。这些高自身荧光系在病程为3年或更短的患者中出现的频率明显更高。在这37只眼中，有23只（62.2%）在术后第一个月内，超自体荧光线消失。高自荧光线的消失被认为是视网膜血管返回到其原始位置的结果。术后1个月超自体荧光线变得模糊的患者的视力改善（最小分辨角的对数，>= 0.3）有统计学意义（P < 0.05）。结论：在ERM手术前66.1%的患者中FAF发现了提示视网膜移位的超自体荧光线。此外，视网膜移位在经历主观症状3年或更短时间的患者中更为常见。眼底自身荧光可用于预测术后视力的改善。(c) 2013年Elsevier Inc.版权所有。)
OBJECTIVE: To study the displacement of the retina and its change after vitrectomy in idiopathic epiretinal membrane (ERM).DESIGN: Prospective, interventional case series.METHODS: Fifty-six eyes of 53 consecutive patients with ERM underwent vitrectomy with ERM removal and internal limiting membrane peeling. Fundus auto-fluorescence (FAF) imaging was examined before and at 1, 3, 6, and 12 months after vitrectomy. Main outcome measures were the proportion of eyes with retinal displacement for ERM detected by FAF imaging and the recovery rate of retinal displacement after vitrectomy.RESULTS: Before surgery, FAF photography demonstrated hyperautofluorescent lines within the vascular arcade in 37 (66.1%) of the 56 eyes. The lines seemed to be consistent with the location of the retinal vessels before their displacement. These hyperautofluorescent lines appeared significantly more frequently among patients in whom the disease duration was 3 years or less. In 23 (62.2%) of these 37 eyes, within the first postoperative month, the hyperautofluorescent lines disappeared. The disappearance of the hyperautofluorescent line was thought to be the result of the return of the retinal vessel to its original position. Greater visual improvements (logarithm of the minimal angle of resolution, >= 0.3) were statistically significantly obtained in patients in whom the hyperautofluorescent lines had become indistinct at 1 month after surgery (P < .05).CONCLUSIONS: Hyperautofluorescent lines indicating retinal displacement were found by FAF in 66.1% of patients before surgery for ERM. In addition, retinal displacement was significantly more common among patients who had experienced subjective symptoms for 3 years or less. Fundus autofluorescence is useful for predicting postoperative visual acuity improvement. ((c) 2013 by Elsevier Inc. All rights reserved.)