Pigmentation Genes Show Evidence of Repeated Divergence and Multiple Bouts of Introgression in Setophaga Warblers
Pigmentation Genes Show Evidence of Repeated Divergence and Multiple Bouts of Introgression in Setophaga Warblers
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DOI：
10.1016/j.cub.2020.10.094
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发表时间：
2021-02-08
期刊：
影响因子：
9.2
通讯作者：
Toews, David P. L.
中科院分区：
文献类型：
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作者：
Baiz, Marcella D.;Wood, Andrew W.;Toews, David P. L.
物种辐射长期以来一直是进化生物学中的模型系统。（1，2）然而，直到最近才有可能研究负责多样化的性状的遗传基础，并且仅在少数模型系统中。(3)在这里，我们使用36种北美，中美洲和南美洲莺的基因组，突出色素沉着基因的作用，参与黑色素和类胡萝卜素加工，在这个群体的多样化。我们发现，agglutinin信号蛋白（ASIP）和β-胡萝卜素加氧酶2（BCO 2）是可预见的分歧物种之间的不同，在他们的羽毛中的黑色素和类胡萝卜素的分布，分别。在物种中，ASIP的序列变异广泛地反映了物种的系统发育史，与产生基于黑色素的变异的重复的独立突变一致。相比之下，BCO 2的变化与物种树高度不一致，有证据表明，在黄莺（Setophaga petechia）和黄莺（S.具有广泛的基于类胡萝卜素的着色。我们还检测到一小部分BCO 2编码区的基因渗入（
Species radiations have long served as model systems in evolutionary biology.(1,2) However, it has only recently become possible to study the genetic bases of the traits responsible for diversification and only in a small number of model systems.(3) Here, we use genomes of 36 species of North, Central, and South American warblers to highlight the role of pigmentation genes-involved in melanin and carotenoid processing-in the diversification of this group. We show that agouti signaling protein (ASIP) and beta-carotene oxygenase 2 (BCO2) are predictably divergent between species that differ in the distribution of melanin and carotenoid in their plumages, respectively. Among species, sequence variation at ASIP broadly mirrors the species' phylogenetic history, consistent with repeated, independent mutations generating melanin-based variation. In contrast, BCO2 variation is highly discordant from the species tree, with evidence of cross-lineage introgression among species like the yellow warbler (Setophaga petechia) and magnolia warbler (S. magnolia) with extensive carotenoid-based coloration. We also detect introgression of a small part of the BCO2 coding region (