Chronic lymphadenopathy due to mycobacterial infection. Clinical features, diagnosis, histopathology, and management.
Chronic lymphadenopathy due to mycobacterial infection. Clinical features, diagnosis, histopathology, and management.
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分枝杆菌感染引起的慢性淋巴结肿大。
DOI：
10.1001/archpedi.1984.02140480019007
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发表时间：
1984
影响因子：
--
通讯作者：
R. Altman
中科院分区：
文献类型：
--
作者：
A. Margileth;R. Chandra;R. Altman
本报告提供了153例分枝杆菌性淋巴结炎的临床信息、诊断标准、治疗和结局; 22例患者（14%）患有结核分枝杆菌（TB），131例患者（86%）患有非结核分枝杆菌（NTM）疾病。正确诊断结核病与非结核性淋巴结炎是必要的，因为抗结核化疗对结核性淋巴结炎是有效的，而切除活检是非结核性淋巴结炎的治疗选择。在153例患者中，151例（99%）患者的双重（PPD-NTM，PPD-T）Mantoux试验区分了TB和NTM腺炎，而在153例患者中，135例（88%）患者的双重（PPD-Battey [B]，PPD-T）试验区分了NTM和TB腺炎。PPD-T反应为1至14 mm提示NTM或TB感染，而PPD-T为15 mm或更大与TB疾病密切相关。我们建议使用PPD-B和PPD-T抗原作为TB和NTM腺炎之间可靠的诊断鉴别剂。
This report provides clinical information, diagnostic criteria, management, and outcome of 153 cases of mycobacterial lymphadenitis; 22 patients (14%) had Mycobacterium tuberculosis (TB) and 131 patients (86%) had nontuberculous mycobacterial (NTM) disease. Correct diagnosis of TB v NTM disease is essential, since antituberculous chemotherapy was effective for TB adenitis, while excisional biopsy was the treatment of choice for NTM adenopathy. Dual (PPD-NTM, PPD-T) Mantoux tests discriminated between TB and NTM adenitis in 151 (99%) of 153 patients, while dual (PPD-Battey [B], PPD-T) tests differentiated between NTM and TB adenitis in 135 (88%) of 153 cases. A PPD-T reaction of 1 to 14 mm suggested either an NTM or TB infection, whereas a PPD-T of 15 mm or greater was strongly associated with TB disease. We recommend the use of PPD-B and PPD-T antigens as reliable diagnostic discriminators between TB and NTM adenitis.