Prevalence of erm(A) and mef(B) erythromycin resistance determinants in isolates of Streptococcus pneumoniae from New Zealand
Prevalence of erm(A) and mef(B) erythromycin resistance determinants in isolates of Streptococcus pneumoniae from New Zealand
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DOI：
10.1093/jac/dkf169
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发表时间：
2002-10-01
影响因子：
5.2
通讯作者：
Klena, JD
中科院分区：
文献类型：
--
作者：
Bean, DC;Klena, JD
对124株红霉素耐药肺炎球菌进行了大环内酯类耐药基因检测。其中118株（95.2%）携带有MEF（B）基因，83株（66.9%）携带有MEF（A）基因。77株（62.1%）同时检测到mef（A）和mef（B）基因。这些菌株的DNA宏观限制性分析确定它们属于一个单一的多抗性克隆。
One hundred and twenty-four erythromycin-resistant pneumococcal isolates were examined for the presence of macrolide resistance genes. The erm(B) gene was detected in 118 (95.2%) isolates and the mef(A) gene in 83 (66.9%) isolates. Both the mef(A) and erm(B) genes were detected in 77 (62.1%) isolates. DNA macrorestriction analysis of these isolates identified them as belonging to a single multi-resistant clone.