Insertion of two pyrene moieties into oligodeoxyribonucleotides for the efficient detection of deletion polymorphisms.
Insertion of two pyrene moieties into oligodeoxyribonucleotides for the efficient detection of deletion polymorphisms.
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DOI：
10.1039/b604776a
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发表时间：
2006-06
影响因子：
4.9
通讯作者：
H. Kashida;H. Asanuma;M. Komiyama
中科院分区：
文献类型：
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作者：
H. Kashida;H. Asanuma;M. Komiyama
为了检测缺失多态，两个芘部分被拴在中间碱基两侧的寡脱氧核苷酸(ODN)上；通过准分子发射的强度可以选择性地检测一个和两个碱基的缺失。
For the detection of deletion polymorphisms, two pyrene moieties are tethered to an oligodeoxyribonucleotide (ODN) on both sides of the intervening base; one- and two-base deletions can be selectively detected by the strength of the excimer emission.