EEG AND EVOKED-POTENTIALS IN A SERIES OF 21 PATIENTS WITH LISSENCEPHALY TYPE-I
EEG AND EVOKED-POTENTIALS IN A SERIES OF 21 PATIENTS WITH LISSENCEPHALY TYPE-I
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DOI：
10.1055/s-2008-1071302
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发表时间：
1992-02-01
期刊：
影响因子：
1.4
通讯作者：
DEWEERD, AW
中科院分区：
文献类型：
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作者：
DERIJKVANANDEL, JF;ARTS, WFM;DEWEERD, AW
21名荷兰患者是I型无脑回畸形广泛研究的对象。研究了这些患者的114例EEG。将EEG与21例非典型皮质发育不良患者记录的52例EEG进行比较，并与823例因各种原因记录的882例EEG组成的对照组进行比较。无脑回畸形患者的脑电图更经常地显示出以下模式：（a）振幅高于50 μ V的广义快活动（8-18/s），（c）振幅高于500 μ V的尖波和慢波复合波，（d）交替模式，由尖波的爆发与脑电抑制的周期交替组成。无脑回畸形患者中有5%表现为（a）型或（c）型或两者兼有，而非典型皮质发育不良患者中只有5%和对照组中只有0.4%。10例患者刺激正中神经后SSEP均异常。EEG和诱发电位对无脑回畸形的诊断有重要价值。I型无脑回畸形的鉴别诊断
Twenty-one Dutch patients were the subject of an extensive study into lissencephaly type I. One hundred and fourteen EEG's of these patients were studied. The EEG's were compared to 52 EEG's recorded from 21 patients with an atypical cortical dysplasia and to a control group consisting of 882 EEG's recorded from 823 patients for various reasons. The EEG's in the lissencephaly patients showed the following patterns significantly more often: (a) generalized fast activity (8-18/s) with an amplitude higher than 50-mu-V, (c) sharp- and slow-wave complexes with an amplitude higher than 500-mu-V, (d) an alternating pattern consisting of bursts of sharp waves alternating with periods of electrocerebral depression.Ninety-five percent of the lissencephaly patients showed pattern (a) or (c) or both compared to only 5% of the patients with an atypical cortical dysplasia and 0.4% in the controls.The SSEP's recorded in ten patients after stimulation of the median nerve were abnormal in all.EEG and evoked potentials appear to be valuable examinations in the (differential) diagnosis of lissencephaly type I.