Physiology, pathology and pharmacology of the male reproductive system

Physiology, pathology and pharmacology of the male reproductive system
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DOI:
10.1111/j.1600-0757.2011.00408.x
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发表时间:
2013-01-01
影响因子:
18.6
通讯作者:
Mariotti, Angelo
Mariotti, Angelo
中科院分区:
医学1区
文献类型:
--
作者:
Mawhinney, Michael;Mariotti, Angelo

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男性生殖系统由睾丸、导管系统和性附属器官组成。睾丸产生的精子与性附属器官(如精囊、前列腺和尿道球腺)形成的液体结合,产生一种分泌物,支持精子的存活,并提供一种介质,精子可通过该介质移动通过生殖管道(如附睾、输精管、射精管和尿道),将活精子射入雌性生殖道。本文综述了正常男性生殖生理的基本知识、男性性分化障碍、常见男性泌尿生殖道疾病的药物治疗以及滥用药物对男性生殖系统的影响。
The male reproductive system consists of the testes, a ductal system and sex accessory organs. Production of sperm by the testes combined with fluids formed by the sex accessory organs (e.g. seminal vesicles, prostate and bulbourethral glands) produce a secretion that supports the survival of spermatozoa and provides a medium through which they can move through the reproductive ducts (e.g. epididymis, vas deferens, ejaculatory duct and urethra) for ejaculation of viable sperm into the female reproductive tract. Summarized herein are the essentials of normal male reproductive physiology, disorders of male sexual differentiation, pharmacological therapy of common diseases of the male genitourinary tract and the impact of drugs of abuse on the male reproductive system.