Prenatal depression and adverse birth outcomes: an updated systematic review.
Prenatal depression and adverse birth outcomes: an updated systematic review.
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DOI：
10.1007/s10995-014-1637-2
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发表时间：
2015-06
影响因子：
2.3
通讯作者：
Schetter, Christine Dunkel
中科院分区：
文献类型：
--
作者：
Accortt, Eynav Elgavish;Cheadle, Alyssa C. D.;Schetter, Christine Dunkel
与早产（PTB）和低出生体重（LBW）相关的并发症是婴儿发病和死亡的主要原因。产前抑郁症是两种出生结果的假设心理社会危险因素。本系统评价的目的是检查 1977 年至 2013 年间发表的有关产前抑郁症和这些主要不良出生结局风险的证据。对 PUBMED 和 PsycINFO 数据库进行了系统检索，以确定测试产前抑郁症状或抑郁诊断与 PTB 或 LBW 风险之间关联的研究。我们系统地筛选了 50 篇已发表的关于 PTB 和妊娠时长的报告，以及 33 篇关于 LBW 和 BW 的报告。结果由两名独立评审员评审，我们使用既定的系统评审方法纽卡斯尔渥太华量表评估了证据的质量。然后，我们按照系统评价和荟萃分析指南的首选报告项目对结果进行了叙述性综合。在 50 份已发表的报告中，不到四分之一发现产前抑郁症与 PTB 或胎龄显着相关。相比之下，33 份报告中略超过一半的报告发现产前抑郁症与低体重或体重相关。在权衡方法学特征时，我们确定产前抑郁症对 LBW 的影响比对妊娠时长或 PTB 的影响更加一致。尽管证据可能不足以支持常规抑郁症筛查以确定不良后果的风险，但有必要进行筛查以发现并及时治疗，以降低产后抑郁症的风险。需要对产前抑郁症和不良分娩结局进行进一步严格的研究。
Complications related to preterm birth (PTB) and low birth weight (LBW) are leading causes of infant morbidity and mortality. Prenatal depression is a hypothesized psychosocial risk factor for both birth outcomes. The purpose of this systematic review was to examine evidence published between 1977 and 2013 on prenatal depression and risks of these primary adverse birth outcomes. A systematic search of the PUBMED and PsycINFO databases was conducted to identify studies testing the associations between prenatal depressive symptoms, or diagnoses of depression, and risk of PTB or LBW. We systematically selected 50 published reports on PTB and length of gestation, and 33 reports on LBW and BW. Results were reviewed by two independent reviewers and we evaluated the quality of the evidence with an established systematic review method, the Newcastle Ottawa Scale. We then undertook a narrative synthesis of the results following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Less than a quarter of 50 published reports found that prenatal depression was significantly associated with PTB or gestational age. In contrast, slightly more than half of the 33 reports found that prenatal depression was associated with LBW or BW. When weighing methodological features, we determined that the effects of prenatal depression on LBW are more consistent than effects on length of gestation or PTB. Although the evidence may not be strong enough to support routine depression screening for risk of adverse outcomes, screening to enable detection and timely treatment to reduce risk of postpartum depression is warranted. Further rigorous research on prenatal depression and adverse birth outcomes is needed.
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影响因子：
4.4
作者：
Burns A;O'Mahen H;Baxter H;Bennert K;Wiles N;Ramchandani P;Turner K;Sharp D;Thorn J;Noble S;Evans J
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10.1177/070674371105600506
发表时间：
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通讯作者：
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DOI：
10.1016/j.ejogrb.2010.08.021
发表时间：
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影响因子：
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作者：
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通讯作者：
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影响因子：
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作者：
BECK, AT;ERBAUGH, J;MENDELSOHN, M
通讯作者：
MENDELSOHN, M