Effect of masticatory function on the internal bone structure in the mandible of the growing rat
Effect of masticatory function on the internal bone structure in the mandible of the growing rat
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DOI：
10.1046/j.0909-8836.1999.eos107107.x
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发表时间：
1999-02-01
影响因子：
1.9
通讯作者：
Strid, KG
中科院分区：
文献类型：
--
作者：
Bresin, A;Kiliaridis, S;Strid, KG
分析了生长期大鼠下颌骨不同功能单位的骨量、骨密度和皮质厚度随咀嚼功能变化的影响。雄性白化病幼鼠分别喂硬食和软食4周。从5个下颌骨区域中选择未脱钙冠状切片，并在铝阶梯楔旁边获得标本的显微放射影像。用计算机辅助图像分析系统测量选定部位的骨量和骨密度。在图表上测量皮质厚度。软食组咀嚼功能的降低在下颌骨的测试区域产生了不同的适应性反应。一些区域显示皮质厚度减少（切牙下方和第一磨牙外侧以及升支的一些位置），一些区域显示骨密度降低（第一磨牙内侧和升支），只有一个区域显示两者（升支）。骨量减少主要与较薄的皮质骨有关，而不是较低的皮质骨密度。皮质厚度的变化和骨密度的变化可能是两种不同的机制来调整局部力学性能的大鼠下颌骨。咀嚼肌功能是决定骨皮质和骨小梁数量和密度的决定因素，并可能影响正畸牙齿移动的结果及其可能的复发。
The influence of changes in the masticatory function on bone mass, bone density and cortical thickness was analyzed in different functional units of the mandible of the growing rat. Young male albino rats were fed either a hard diet or a soft diet for 4 wk. Undecalcified coronal sections were selected from five mandibular regions and microradiographic images of the specimens alongside an aluminium stepwedge were obtained. Bone mass and density were measured at selected sites with a computer-aided image analysis system. Cortical thickness was measured on diagrams. The reduced masticatory function in the soft diet group produced different adaptive responses in the tested regions of the mandible. Some regions showed reduced cortical thickness (underneath the incisor and lateral to the first molar and some locations of the ramus), a few showed reduced bone density (medial to the first molar and in the ramus), and only one showed both (in the ramus). Reduced bone mass was associated mostly with thinner cortical bone rather than lower cortical bone density. Changes in cortical thickness and changes in bone density may be two different mechanisms for adjusting local mechanical properties in the mandible of the rat. Masticatory muscle function is a determinant for the amount and density of cortical and trabecular bone and may possibly influence results of orthodontic tooth movement and its possible relapse.