Why permutation tests are superior to t and F tests in biomedical research
Why permutation tests are superior to t and F tests in biomedical research
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DOI：
10.2307/2685470
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发表时间：
1998-05-01
影响因子：
1.8
通讯作者：
Dudley, H
中科院分区：
文献类型：
--
作者：
Ludbrook, J;Dudley, H
一项对五种经常被引用的生物医学期刊上报道的252项前瞻性比较研究的调查显示，96%的实验组是通过随机化建立的，只有4%的实验组是通过随机抽样建立的。中位组大小范围为4至12。在随机化研究中，测量是在一个连续的规模，比较的位置进行了t或F检验的情况下，84%，其余的非参数，秩和检验。由于随机化而不是随机抽样是生物医学研究中的规范，并且由于组的大小通常很小，因此对于位置差异的精确排列或随机化检验应优于t或F检验。
A survey of 252 prospective, comparative studies reported in five, frequently cited biomedical journals revealed that experimental groups were constructed by randomization in 96% of cases and by random sampling in only 4%. The median group sizes ranged from 4 to 12. In the randomized studies in which measurements were made on a continuous scale, comparisons of location were made by t or F tests in 84% of cases, and by nonparametric, rank-order, tests in the remainder. Because randomization rather than random sampling is the norm in biomedical research and because group sizes are usually small, exact permutation or randomization tests for differences in location should be preferred to t or F tests.