Pseudocontinuous arterial spin labeling with prospective motion correction (PCASL-PROMO).
Pseudocontinuous arterial spin labeling with prospective motion correction (PCASL-PROMO).
复制标题
DOI：
10.1002/mrm.25024
复制
发表时间：
2014-10
影响因子：
3.3
通讯作者：
Zaharchuk, Greg
中科院分区：
文献类型：
--
作者：
Zun, Zungho;Shankaranarayanan, Ajit;Zaharchuk, Greg
具有分段三维（3D）读出的动脉自旋标记（ASL）灌注成像正变得越来越流行，然而传统的运动校正方法不能应用于分段成像中。本研究的目的是证明3D伪连续ASL（PCASL）和PROMO（前瞻性运动校正）用于脑血流量测量的整合。PROMO集成到3D PCASL中，而不增加重复时间。在无运动的情况下，使用和不使用PROMO进行PCASL。然后，使用带有和不带有PROMO的单独扫描的受控运动，以及使用交错扫描的随机运动，评价PCASL-PROMO的性能，其中每个重复时间重复两次，一次带有PROMO，一次不带有PROMO。常规和PROMO实现之间的3D体积的平均ASL信号的差异可以忽略不计（<0.2%）。来自受控和随机运动的ASL图像伪影均通过PROMO显著去除，显示出与参考图像的改善的相关性。使用交错扫描采集的数据的多种组合显示，仅使用实时运动更新的PROMO显著减少了运动伪影，并且在标记图像中重新扫描损坏的片段比对照图像更重要。这项研究表明，PROMO是一种成功的方法来运动校正PCASL脑血流成像。
Arterial spin labeling (ASL) perfusion imaging with a segmented three-dimensional (3D) readout is becoming increasing popular, yet conventional motion correction approaches cannot be applied in segmented imaging. The purpose of this study was to demonstrate the integration of 3D pseudocontinuous ASL (PCASL) and PROMO (PROspective MOtion correction) for cerebral blood flow measurements. PROMO was integrated into 3D PCASL without increasing repetition time. PCASL was performed with and without PROMO in the absence of motion. The performance of PCASL-PROMO was then evaluated with controlled motions using separate scans with and without PROMO and also with random motion using an interleaved scan where every repetition time is repeated twice, once with and once without PROMO. The difference in the average ASL signal of the 3D volume between conventional and PROMO implementations was negligible (<0.2%). ASL image artifacts from both controlled and random motions were removed significantly with PROMO, showing improved correlation with reference images. Multiple combinations of data acquired using the interleaved scan revealed that PROMO with real-time motion updating alone reduces motion artifact significantly and that rescanning of corrupted segments is more critical in tagged images than control images. This study demonstrates that PROMO is a successful approach to motion correction for PCASL cerebral blood flow imaging.
登录
查看更多内容
影响因子：
3.3
作者：
Keating, Brian;Deng, Weiran;Roddey, J. Cooper;White, Nathan;Dale, Anders;Stenger, V. Andrew;Ernst, Thomas
通讯作者：
Ernst, Thomas
影响因子：
2.5
作者：
HAACKE E M;PATRICK J L
通讯作者：
PATRICK J L
影响因子：
2.5
作者：
Wang, Ze;Aguirre, Geoffrey K.;Detre, John A.
通讯作者：
Detre, John A.
影响因子：
3.3
作者：
Petersen, ET;Lim, T;Golay, X
通讯作者：
Golay, X
影响因子：
3.3
作者：
Lawrence, KSS;Wang, J
通讯作者：
Wang, J