Efficient methylation of carboxylic acids with potassium hydroxide/methyl sulfoxide and iodomethane

Efficient methylation of carboxylic acids with potassium hydroxide/methyl sulfoxide and iodomethane
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DOI:
10.1081/scc-100104469
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发表时间:
2001-01-01
影响因子:
2.1
通讯作者:
Martínez, R
Martínez, R
中科院分区:
化学4区
文献类型:
--
作者:
Avila-Zárraga, JG;Martínez, R

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在甲基亚砜和碘甲烷中,氢氧化钾促进几种羧酸的甲基化,生成相应的甲酯,收率高。该方法的优点在于它使用便宜的试剂,反应在温和和有利的条件下进行。
Methylation of several carboxylic acids was promoted by potassium hydroxide in methyl sulfoxide and iodomethane to produce corresponding methyl esters in good yield. This method has advantage over other described methods because it uses inexpensive reagents and the reaction is carried out under mild and favorable conditions.