Pancreatic and peripancreatic tuberculosis presenting as hypoechoic mass and malignancy diagnosed by ultrasound-guided fine-needle aspiration cytology.
Pancreatic and peripancreatic tuberculosis presenting as hypoechoic mass and malignancy diagnosed by ultrasound-guided fine-needle aspiration cytology.
复制标题
DOI：
10.4103/0970-9371.112658
复制
发表时间：
2013-04
影响因子：
1.3
通讯作者：
Gupta A
中科院分区：
文献类型：
--
作者：
Rao RN;Pandey R;Rana MK;Rai P;Gupta A
胰腺及胰周结核是一种极为少见的疾病，超声表现为低回声肿块，影像学上酷似恶性肿瘤。因此，这是一个诊断上的挑战。研究2006年至2010年5年间14例接受超声/内镜引导下细针穿刺细胞学（FNAC）检查的胰腺和胰周结核罕见病例。在2例患者中进行了内镜引导下的FNAC，而在12例患者中使用22-G针通过经皮经腹途径进行了超声引导下的FNAC。将吸出的材料快速涂抹在载玻片上，风干，并在95%乙醇中湿固定，用于随后的巴氏染色。胰腺及胰周结核均表现为胰腺囊实性肿块。涂片显示上皮样细胞肉芽肿、多核巨细胞、混合炎性细胞和坏死背景下的组织细胞。常见的解剖部位为胰头、胰周、胰尾和胰体。超声/内镜引导下细针穿刺活检是胰腺及胰周结核术前诊断的一种安全、可靠、经济的方法。胰腺和胰周结核的临床症状和超声/内镜引导下FNAC的准确诊断方法是必要的，以避免重复剖腹手术。尽管罕见，胰腺和胰周结核应考虑在地方性发展中国家的胰腺和胰周囊性肿块的鉴别诊断。
Pancreatic and peripancreatic tuberculosis is an extremely uncommon disease, presenting as hypoechoic mass on ultrasonography and imaging mimicking malignancy. Consequently, it represents a diagnostic challenge. To study 14 unusual cases of pancreatic and peripancreatic tuberculosis undergoing ultrasound-/endoscopic-guided fine-needle aspiration cytology (FNAC) in the 5-year period from 2006 to 2010. Endoscopic-guided FNAC was done in two cases, while ultrasound-guided FNAC was performed in 12 cases using 22-G needles via a percutaneous transabdominal approach. The aspirated material was quickly smeared onto glass slides, air dried, and wet fixed in 95% ethyl alcohol for subsequent Papanicolaou staining. All pancreatic and peripancreatic tuberculosis cases showed solid-cystic pancreatic mass. Smears showed epithelioid cell granulomas, multinucleated giant cells, mixed inflammatory cells and histiocytes against a necrotic background. The common anatomic locations were the head, peripancreatic, tail and body of the pancreas. Ultrasound-/endoscopic-guided FNAC is a safe, reliable and cost-effective method for preoperative diagnosis of pancreatic and peripancreatic tuberculosis. Clinical symptoms and accurate diagnostic approach by ultrasound-/endoscopic-guided FNAC of pancreatic and peripancreatic tuberculosis is needed to avoid performing redundant laparotomy. Despite its rarity, pancreatic and peripancreatic tuberculosis should be considered for differential diagnosis of pancreatic and peripancreatic cystic mass in endemic developing countries.
登录
查看更多内容
影响因子：
2.7
作者：
Evans, JD;Hamanaka, Y;Neoptolemos, JP
通讯作者：
Neoptolemos, JP
影响因子：
9.6
作者：
FAN, ST;YAN, KW;WONG, KK
通讯作者：
WONG, KK
影响因子：
3.1
作者：
Rezeig, MA;Fashir, BM;Eisa, H
通讯作者：
Eisa, H
影响因子：
3.6
作者：
Schneider, A;von Birgelen, C;Rünzi, M
通讯作者：
Rünzi, M
影响因子：
6.3
作者：
Itaba, Soichi;Yoshinaga, Shigetaka;Yamada, Kinya
通讯作者：
Yamada, Kinya