The coding of odour-intensity in the honeybee antennal lobe: local computation optimizes odour representation
The coding of odour-intensity in the honeybee antennal lobe: local computation optimizes odour representation
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DOI：
10.1046/j.1460-9568.2003.02931.x
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发表时间：
2003-10-01
影响因子：
3.4
通讯作者：
Galizia, CG
中科院分区：
文献类型：
--
作者：
Sachse, S;Galizia, CG
我们调查的策略参与气味强度编码的主要嗅觉中心的昆虫，触角叶（AL），嗅球的结构和功能类似物。使用钙成像的蜜蜂，我们同时测量的投射神经元的输出反应和复合信号为主的受体神经元输入确定的嗅球的气味跨越7个对数单位的浓度。两个处理水平的比较表明，AL内的细胞间计算调制和对比度增强的主要嗅觉信号。因此，AL网络优化了嗅觉代码：气味表示在较低浓度下得到改善，嗅球的相对活性允许编码气味质量超过四个对数单位浓度，并且气味强度可靠地表示在整个AL的整体激发中。
We investigated strategies involved in odour intensity coding by the primary olfactory centre of insects, the antennal lobe (AL), the structural and functional analogue of the olfactory bulb. Using calcium imaging in the honeybee, we simultaneously measured the projection neuron output responses and a compound signal dominated by receptor neuron input in identified olfactory glomeruli to odours spanning seven log units of concentration. A comparison of the two processing levels indicates that the intercellular computation within the AL modulates and contrast-enhances the primary olfactory signals. As a result the AL network optimizes the olfactory code: odour representation is improved at lower concentrations, the relative activity of olfactory glomeruli allows encoding odour quality over up to four log-unit concentrations, and odour-intensity is reliably represented in the overall excitation across AL.