Reliability of motor-evoked potentials during resting and active contraction conditions
Reliability of motor-evoked potentials during resting and active contraction conditions
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DOI：
10.1249/01.mss.0000139804.02576.6a
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发表时间：
2004-09-01
期刊：
影响因子：
--
通讯作者：
Kamen, G
中科院分区：
文献类型：
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作者：
Kamen, G
目的：目的：探讨经颅磁刺激（TMS）在第一骨间背侧肌（FDI）和肱二头肌中获得的运动诱发电位（MEP）的可靠性。方法：14名大学受试者参加了实验室在三个不同的日子。TMS用于获得MEP，受试者放松（静息状态），刺激强度为最大刺激器输出的70%、85%和100%。MEP也在四种主动收缩条件下获得，包括25%，50%，75%和100%的最大努力（MVC）的收缩。采用组内相关方差分析（ANOVA）设计测量可靠性。结果：在静息状态下，MEP振幅的大幅增加，观察到两个肌肉从第1天到第2天。肱二头肌（ICC = 0.95-0.99）的组内可靠性估计值高于FDI肌肉（ICC = 0.60-0.81）。在活动条件下，在25%和50%MVC时观察到最大MEP，在75%和100%MVC时观察到较小MEP。活动状态下的组内相关性约为0.63-0.73。结论：在静息和主动收缩条件下，使用TMS可以获得二头肌和FDI肌肉中MEP幅度的中等至良好的可靠性。
Purpose: To determine the reliability of motor-evoked potentials (MEP) obtained using transcranial magnetic stimulation (TMS) in the first dorsal interosseous (FDI) and biceps brachii muscles. Methods: Fourteen college subjects attended the laboratory on three separate days. TMS was used to obtain MEP with the subject relaxed (resting condition) at stimulation intensities of 70%, 85%, and 100% of maximal stimulator output. MEP were also obtained during four active contraction conditions involving contractions of 25%, 50%, 75%, and 100% of maximal effort (MVC). Reliability was measured using an intraclass correlation analysis of variance (ANOVA) design. Results: In the resting condition, substantial increases in MEP amplitude were observed for both muscles from day 1 to day 2. Intraclass reliability estimates were higher for the biceps muscle (ICC = 0.95-0.99) than for the FDI muscle (ICC = 0.60-0.81). During the active conditions, the greatest MEP were observed at 25% and 50% MVC, with smaller MEP at 75% and 100% MVC. Intraclass correlations in the active condition were approximately 0.63-0.73. Conclusions: Moderate to good reliability of MEP amplitude in the biceps and FDI muscles can be obtained using TMS in both resting and active contraction conditions.