NESTED CASE-CONTROL AND CASE-COHORT METHODS OF SAMPLING FROM A COHORT - A CRITICAL COMPARISON
NESTED CASE-CONTROL AND CASE-COHORT METHODS OF SAMPLING FROM A COHORT - A CRITICAL COMPARISON
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DOI：
10.1093/oxfordjournals.aje.a115471
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发表时间：
1990-01-01
影响因子：
5
通讯作者：
THOMAS, DC
中科院分区：
文献类型：
--
作者：
LANGHOLZ, B;THOMAS, DC
对新近发展的病例队列抽样法与嵌套式病例对照方法进行了比较。修正的渐近相对效率结果表明，对于不存在随机审查的干预试验，单一“疾病”结果的病例队列设计提供的改善比最初建议的要小。此外，模拟结果表明，如果有适度的随机删减或交错条目，病例队列方法的效果可能比嵌套病例对照方法差得多。
The recently developed case-cohort method of sampling from a cohort is compared with the nested case-control method. Corrected asymptotic relative efficiency results show that the case-cohort design for single "disease" outcomes offers less improvement for intervention trials for which there is no random censoring than originally suggested. Furthermore, simulation results indicate that if there is moderate random censoring or staggered entry, the case-cohort method can do substantially worse than the nested case-control method.