Studies of Retinopathy: Methodology for Assessment and Classification with Fundus Photographs
Studies of Retinopathy: Methodology for Assessment and Classification with Fundus Photographs
复制标题
视网膜病变研究：利用眼底照片进行评估和分类的方法
作者：
M. Davis;L. Hubbard;James Trautman;R. Klein
这项研究的一个主要目标是评估适用于代谢管理试验的视网膜病变定量方法。我们描述了用于分级立体彩色眼底照片的方法。根据单个病变的分级，对每只眼睛的总体视网膜病变严重程度进行了分配，范围从正常（10级）到高风险类别（70级）。根据使用的方法和变化的定义，在3-62%的患者中检测到8个月期间视网膜病变严重程度的变化。病变负责的水平变化主要是视网膜梗死（软渗出液）和视网膜内微血管异常。
A major goal of the study was to assess the methodologies available for the quantification of retinal lesions suitable for application in trials of metabolic management. We describe the methods used for grading stereoscopic color fundus photographs. Overall retinopathy severity level for each eye ranging from normal (level 10) to high-risk category (level 70) was assigned on the basis of gradings of individual lesions. Change in retinopathy severity level over the 8-mo period was detected in 3–62% of patients, depending on the method used and the definition of change. Lesions responsible for change in level were mainly retinal infarcts (soft exudates) and intraretinal microvascular abnormalities.