Methicillin-resistant Staphylococcus aureus in horses and horse personnel, 2000-2002
Methicillin-resistant Staphylococcus aureus in horses and horse personnel, 2000-2002
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DOI：
10.3201/eid1103.040481
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发表时间：
2005-03-01
影响因子：
11.8
通讯作者：
Low, DE
中科院分区：
文献类型：
--
作者：
Weese, JS;Archambault, M;Low, DE
2000年，在一家兽医医院治疗的2匹马中发现了耐甲氧西林金黄色葡萄球菌（MRSA）感染，促使对马和相关人员的定植率进行研究。从2000年10月至2002年11月，确定了79匹马和27人定植或感染MRSA;大多数隔离发生在2002年的3个月内。27（34%）个马分离株来自兽医院，而41（51%）个马分离株来自安大略的1个纯种马农场。27株人分离株中有17株（63%）来自兽医院，8株（30%）来自良种场。13匹（16%）马和1名（4%）人出现临床感染。96%的马和93%的人分离株是加拿大流行性MRSA-5的亚型，SPA 7型，并具有SCCmecIV。所有来自临床感染的测试分离株均为Panton-Valentine杀白细胞素基因阴性。马MRSA感染可能是一种重要的新发人畜共患病和兽医学疾病。
Methicillin-resistant Staphylococcus aureus (MRSA) infection was identified in 2 horses treated at a veterinary hospital in 2000, prompting a study of colonization rates of horses and associated persons. Seventy-nine horses and 27 persons colonized or infected with MRSA were identified from October 2000 to November 2002; most isolations occurred in a 3-month period in 2002. Twenty-seven (34%) of the equine isolates were from the veterinary hospital, while 41 (51%) were from 1 thoroughbred farm in Ontario. Seventeen (63%) of 27 human isolates were from the veterinary hospital, and 8 (30%) were from the thoroughbred farm. Thirteen (16%) horses and 1 (4%) person were clinically infected. Ninety-six percent of equine and 93% of human isolates were subtypes of Canadian epidemic MRSA-5, spa type 7 and possessed SCCmecIV. All tested isolates from clinical infections were negative for the Panton-Valentine leukocidin genes. Equine MRSA infection may be an important emerging zoonotic and veterinary disease.