Left Ventricular Assist Device Support and Myocardial Recovery in Recent Onset Cardiomyopathy
Left Ventricular Assist Device Support and Myocardial Recovery in Recent Onset Cardiomyopathy
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DOI：
10.1016/j.cardfail.2012.08.001
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发表时间：
2012-10-01
影响因子：
6
通讯作者：
McNamara, Dennis M.
中科院分区：
文献类型：
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作者：
Boehmer, John P.;Starling, Randall C.;McNamara, Dennis M.
背景：左心辅助装置(LVAD)作为恢复桥梁(BTR)的支持在慢性心力衰竭患者中并不常见。心肌恢复在新近发病的非缺血性心肌病(ROCM)中更为明显；然而，BTR在这一亚组中的患病率尚未得到解决。方法和结果：我们研究了在干预心肌炎和急性心肌病2(IMAC2)研究中，对ROCM受试者使用LVAD支持的情况。总体队列(n=373)中女性占38%，黑人占21%，平均年龄为45岁+/-14岁。3.8%(14例，女性43%，年龄32+/-10岁)使用了左前降支支架。在LVAD患者中，57%(8/14)为BTR，包括73%(8/11)有症状的患者
Background: Left ventricular assist device (LVAD) support as bridge to recovery (BTR) is uncommon for subjects with chronic heart failure. Myocardial recovery is more evident in recent onset nonischemic cardiomyopathy (ROCM); however, the prevalence of BTR in this subset has not been addressed.Methods and Results: We examined the use of LVAD support for subjects with ROCM in the Intervention in Myocarditis and Acute Cardiomyopathy 2 (IMAC2) study. The overall cohort (n = 373) was 38% female, 21% black, with a mean age of 45 +/- 14 years. LVAD support was used in 3.8% (n = 14, 43% female, age 32 +/- 10). Of LVAD subjects, 57% (8/14) were BTR, including 73% (8/11) of subjects with symptoms