Electromagnetic field exposures and childhood cancers in New Zealand
Electromagnetic field exposures and childhood cancers in New Zealand
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DOI：
10.1023/a:1008825220759
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发表时间：
1998-05-01
影响因子：
2.3
通讯作者：
Herbison, GP
中科院分区：
文献类型：
--
作者：
Dockerty, JD;Elwood, JM;Herbison, GP
目的：评估电磁场（EMF）暴露的儿童癌症风险。方法：在新西兰进行病例对照研究。病例（年龄从0岁到14岁）是从包括新西兰癌症登记处在内的国家数据库中确定的；303人参加（参与率88%）。从出生记录中随机选择303名年龄和性别匹配的对照组（参与率69%）。研究人员对母亲进行了器具暴露的访谈（所有病例和对照组），并对24小时居住电磁场进行了测量（白血病病例和匹配的对照组）。结果：对于不同的器具暴露，有一些比值比（OR）高于1.0，而另一些则低于1.0。对于诊断前使用电热毯的儿童，调整后的or为：白血病，2.2(95%可信区间[CI] = 0.7-6.4)；中枢神经系统癌，or = 1.6 (CI = 0.4-7.1)；和其他实体癌，OR = 2.4 （CI = 1.0-6.1）。平均测量的卧室磁场最高类别（大于或等于0.2 μ T cf < 0.1 μ T）的白血病风险增加，调整后or为15.5 （CI = 1.1-224）。没有显示OR与暴露的梯度（中间类别：OR 1.4, CI = 0.3-7.6），并且与基于对照组暴露的三分之一的暴露没有关联。白血病与日间房间磁场（大于或等于0.2 μ T cf < 0.1 μ T）的校正OR为5.2 （CI = 0.9-30.8）。结论：这是一项小型研究，并进行了多次比较。因此，应该谨慎地解释这些积极的发现。
Objectives: To assess childhood cancer risks for electromagnetic field (EMF) exposures.Methods: A case-control study was conducted in New Zealand. Cases (aged from zero to 14 years) were ascertained from national databases including the New Zealand Cancer Registry; 303 took part (participation rate, 88 percent). The 303 age- and gender-matched controls were selected randomly from birth records (participation, 69 percent). Mothers were interviewed about appliance exposures (all cases and controls), and 24-hour residential measurements of EMFs were made (leukemia cases and matched controls),Results: For the various appliance exposures, there were some odds ratios (OR) above 1.0 and others below 1.0. For electric blanket use by the child before diagnosis, the adjusted ORs were: leukemia, 2.2 (95 percent confidence interval [CI] = 0.7-6.4); central nervous system cancers, ORs = 1.6 (CI = 0.4-7.1); and other solid cancers, OR = 2.4 (CI = 1.0-6.1). Leukemia risk was increased for the highest category of the mean measured bedroom magnetic field (greater than or equal to 0.2 mu T cf < 0.1 mu T), with an adjusted OR of 15.5 (CI = 1.1-224). A gradient in OR with exposure was not shown (middle category: OR 1.4, CI = 0.3-7.6), and there was no association with exposure categorized into thirds based on controls' exposure. The adjusted OR for leukemia in relation to the measured daytime room magnetic field (greater than or equal to 0.2 mu T cf < 0.1 mu T) was 5.2 (CI = 0.9-30.8).Conclusions: This was a small study and multiple comparisons were made. The positive findings thus should be interpreted cautiously.