DNA Prism Structures Constructed by Folding of Multiple Rectangular Arms

DNA Prism Structures Constructed by Folding of Multiple Rectangular Arms
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DOI:
10.1021/ja904252e
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发表时间:
2009-11-04
影响因子:
15
通讯作者:
Sugiyama, Hiroshi
Sugiyama, Hiroshi
中科院分区:
化学1区
文献类型:
--
作者:
Endo, Masayuki;Hidaka, Kumi;Sugiyama, Hiroshi

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利用二维DNA折纸支架设计了新型的多臂DNA结构,并将这些结构折叠成中空的三维结构。(3D)通过将连接股线引入臂中来形成结构。通过高速AFM成像检查棱镜结构的开口,其显示3D结构中的连接臂的解离。
Novel multiarm DNA structures were designed using two-dimensional DNA origami scaffolds, and these structures were folded into hollow three-dimensional. (3D) structures by introducing connection strands into the arms. The opening of the prism structures was examined by high-speed AFM imaging, which showed the dissociation of the connecting arms in the 3D structures.