Clinical Applications of Photon-counting CT: A Review of Pioneer Studies and a Glimpse into the Future.
Clinical Applications of Photon-counting CT: A Review of Pioneer Studies and a Glimpse into the Future.
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光子计数 CT 的临床应用：先驱研究回顾和未来展望。
DOI：
10.1148/radiol.222432
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发表时间：
2023
期刊：
影响因子：
19.7
通讯作者：
Budde,RicardoPJ
中科院分区：
文献类型：
--
作者：
Douek,PhilippeC;Boccalini,Sara;Oei,EdwinHG;Cormode,DavidP;Pourmorteza,Amir;Boussel,Loic;Si-Mohamed,SalimA;Budde,RicardoPJ
配备光子计数探测器 (PCD) 的 CT 系统（称为光子计数 CT (PCCT)）正开始改变心脏、血管、胸部和肌肉骨骼放射学等多个亚专业的成像。文献中不断积累的证据支持 PCCT 在不同临床应用中的诸多优势。这些优点源自 PCD 的独特特征，PCD 由能够将光子直接转换为电信号的半导体材料制成。 PCCT 的最重要的进步包括改进的空间分辨率、降噪和光谱特性。 PCCT 空间分辨率约为 0.25 毫米，可以改善小结构（例如小血管、动脉壁、远端支气管和骨小梁）及其病理的可视化，以及识别以前无法检测到的异常。此外，来自钙化、支架和其他致密结构的晕染伪影也减少了。 PCCT 光谱功能的好处是广泛的，包括减少患者的辐射和造影剂剂量。此外，可以从单个数据集（即多参数成像）中提取多种类型的信息，包括通常被视为功能信息（例如，肺灌注）替代物的定量数据。 PCCT 还支持一种新型 CT 成像，即 K 边缘成像。该技术与专门为此模式设计的新型对比材料相结合，为未来成像的新应用打开了大门。© RSNA，2023
CT systems equipped with photon-counting detectors (PCDs), referred to as photon-counting CT (PCCT), are beginning to change imaging in several subspecialties, such as cardiac, vascular, thoracic, and musculoskeletal radiology. Evidence has been building in the literature underpinning the many advantages of PCCT for different clinical applications. These benefits derive from the distinct features of PCDs, which are made of semiconductor materials capable of converting photons directly into electric signal. PCCT advancements include, among the most important, improved spatial resolution, noise reduction, and spectral properties. PCCT spatial resolution on the order of 0.25 mm allows for the improved visualization of small structures (eg, small vessels, arterial walls, distal bronchi, and bone trabeculations) and their pathologies, as well as the identification of previously undetectable anomalies. In addition, blooming artifacts from calcifications, stents, and other dense structures are reduced. The benefits of the spectral capabilities of PCCT are broad and include reducing radiation and contrast material dose for patients. In addition, multiple types of information can be extracted from a single data set (ie, multiparametric imaging), including quantitative data often regarded as surrogates of functional information (eg, lung perfusion). PCCT also allows for a novel type of CT imaging, K-edge imaging. This technique, combined with new contrast materials specifically designed for this modality, opens the door to new applications for imaging in the future.© RSNA, 2023