Mother-to-child transmission of hepatitis B virus. Present knowledge and prevention.
Mother-to-child transmission of hepatitis B virus. Present knowledge and prevention.
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DOI：
10.1016/s0929-693x(00)80199-2
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发表时间：
2000-08-01
影响因子：
1.8
通讯作者：
Bouazzaou, NL
中科院分区：
文献类型：
--
作者：
Hamdani-Belghiti, S;Bouazzaou, NL
B型肝炎病毒（HBV）感染是一个世界性的公共卫生问题。母婴传播是维持感染的主要因素，通常在分娩期间传播，HBV传播的风险取决于母体感染的程度，病毒的基因组类型和母体抗体的比率。一旦母亲在怀孕期间被诊断出感染HBV，现有的预防母婴传播病毒的手段是有效的;在新生儿早期对婴儿联合接种疫苗和特异性免疫球蛋白可以有效地预防母婴传播病毒。(C)2000年，Elsevier SAS科学与医学版。
Hepatitis B virus (HBV) infection is a worldwide problem of public health. Mother/child transmission of the virus represents a major factor in maintaining the infection, which is often transmitted during delivery the risk of transmission of the HBV depending on the degree of maternal infectiosity, the genomic type of the virus, and the rate of maternal antibodies. Evolution towards chronicity of the infected newborn is frequent The available means to prevent the mother/child transmission of the virus are efficient Once HBV maternal infection is diagnosed during pregnancy; joint administration of vaccine and specific immunoglobulins to the baby in the early neonatal period efficiently prevent the mother/child transmission of the virus. (C) 2000 Editions scientifiques et medicales Elsevier SAS.