Basic concepts of optical mapping techniques in cardiac electrophysiology.

Basic concepts of optical mapping techniques in cardiac electrophysiology.
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心脏生理学中光学映射技术的基本概念。

DOI:
10.1177/1099800409338516
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发表时间:
2009-10
影响因子:
2.5
通讯作者:
Clusin WT
Clusin WT
中科院分区:
医学4区
文献类型:
--
作者:
Attin M;Clusin WT

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光学标测是心脏电生理学中用于研究心脏正常节律和心律失常的工具。光学映射技术提供了一个独特的机会,获得膜电位记录具有更高的时间和空间分辨率比电映射。此外,它允许同时记录整个心脏中的膜电位和钙瞬变。本文介绍了光学测绘技术的基本概念,为不熟悉光学测绘技术的实验室的学生和研究人员提供了一个介绍。
Optical mapping is a tool used in cardiac electrophysiology to study the heart's normal rhythm and arrhythmias. The optical mapping technique provides a unique opportunity to obtain membrane potential recordings with a higher temporal and spatial resolution than electrical mapping. Additionally, it allows simultaneous recording of membrane potential and calcium transients in the whole heart. This article presents the basic concepts of optical mapping techniques as an introduction for students and investigators in experimental laboratories unfamiliar with it.
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