Neuropsychological outcomes after psychosocial intervention for depression in Parkinson's disease.
Neuropsychological outcomes after psychosocial intervention for depression in Parkinson's disease.
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帕金森病抑郁症心理社会干预后的神经心理学结果。
DOI：
10.1176/appi.neuropsych.12120381
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发表时间：
2014
期刊：
影响因子：
--
通讯作者：
Menza,Matthew
中科院分区：
文献类型：
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作者：
Dobkin,RoseanneD;Tröster,AlexanderI;Rubino,JadeTiu;Allen,LesleyA;Gara,MichaelA;Mark,MargeryH;Menza,Matthew
作者描述了帕金森病（PD）患者在参与NIH赞助的抑郁症认知行为治疗的随机对照试验后的神经心理学结果。在10周的治疗期间，情绪的改善与言语记忆和执行功能的适度增加相关，并且在治疗结束时，与PD中认知功能的其他已知相关因素（如疾病严重程度，年龄和教育程度）相比，神经心理学结果的差异更大。随着时间的推移，基线工作记忆和执行技能也与抑郁症的改善有关。
The authors describe neuropsychological outcomes in people with Parkinson’s disease (PD) after their participation in an NIH-sponsored, randomized, controlled trial of cognitive-behavioral treatment for depression. Improvements in mood were associated with modest gains in verbal memory and executive functioning over the 10-week treatment period and accounted for greater variance in neuropsychological outcomes at the end of treatment than other known correlates of cognitive functioning in PD, such as disease severity, age, and education. Baseline working memory and executive skills were also associated with depression improvement over time.