Behavioral effects of long-term exposure to a mixture of organic solvents.

Behavioral effects of long-term exposure to a mixture of organic solvents.
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长期接触有机溶剂混合物的行为影响。

DOI:
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发表时间:
1976
期刊:
Scandinavian Journal of Work, Environment and Health
影响因子:
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通讯作者:
Markku Mikael Nurminen
Markku Mikael Nurminen
中科院分区:
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文献类型:
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作者:
H. Hänninen;L. Eskelinen;K. Husman;Markku Mikael Nurminen

文献摘要

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长期暴露于有机溶剂的混合物的行为影响进行了研究,在100名汽车油漆工的测试结果与参考组的比较。成套测试包括智力、记忆力、心理表现和个性测试。除了平均结果的比较,两个判别函数分析。在一个,只有性能测试变量,但在其他人格变量也包括在内。结果表明,暴露组的心理表现受损,以及个性变化。视觉智力和言语记忆的损害以及情绪反应的减少是溶剂暴露的不利影响的中心特征,但行为障碍还涉及其他几个功能,包括言语智力测试的表现。在最初的智力水平的差异可能的作用进行了控制与33对暴露和非暴露的主题谁是匹配的年龄和他们的智力水平,在服兵役期间测量的测试结果的单独比较。判别函数分析是基于这些匹配的亚组的结果,并在其余的材料进行了测试。根据结果,心理测试方法的灵敏度高,但特异性有点低,关于溶剂暴露。汽车油漆工接触的各种溶剂的浓度很低,接触的总和相当于芬兰阈值限值的32%。的溶剂在发展中的行为障碍的增强作用的可能作用进行了讨论。
The behavioral effects of long-term exposure to a mixture of organic solvents were investigated in a comparison of the test results of 100 car painters with those of a reference group. The test battery included tests for intelligence, memory, psychomotor performances, and personality. In addition to the comparison of the mean results, two discriminant function analyses were made. In one, only the performance test variables were used, but in the other personality variables were also included. The results indicated impairments in psychological performances, as well as personality changes in the exposed group. Impairments in visual intelligence and verbal memory and a reduction of emotional reactivity were the central features of the adverse effects of solvent exposure, but the behavioral disturbances also involved several other functions, including performance on a verbal intelligence test. The possible role of the differences in the initial intelligence levels were controlled with a separate comparison of the test results of 33 pairs of exposed and nonexposed subjects who were matched for age and for their intelligence level, measured during the military service. The discriminant function analyses were based on the results of these matched subgroups and tested in the rest of the material. According to the results the sensitivity of the psychological test methods was high, but the specificity somewhat low, with regard to solvent exposure. The concentration of various solvents included in the exposure of car painters were low, the summated exposure corresponding corresponding to 32% of the Finnish threshold limit value. The possible role of a potentiating effect of the solvent in the development of behavioral disturbances is discussed.