SIZE AND HISTOLOGICAL APPEARANCES OF MESENTERIC LYMPH-NODES IN CROHNS-DISEASE

SIZE AND HISTOLOGICAL APPEARANCES OF MESENTERIC LYMPH-NODES IN CROHNS-DISEASE
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DOI:
10.1136/gut.13.12.970
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发表时间:
1972-01-01
期刊:
GUT
影响因子:
24.5
通讯作者:
COOK, MG
COOK, MG
中科院分区:
医学1区
文献类型:
--
作者:
COOK, MG

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在34例克罗恩病标本中,相关淋巴结的大小及其组织学相关。肉芽肿不影响淋巴结的最大直径,也不常见于大淋巴结。淋巴结肿大似乎是由于简单的、非特异性的反应性变化。肉芽肿性淋巴结在我们所有克罗恩病病例中占38%,在肠壁肉芽肿病例中占63%。1例淋巴结内发现肉芽肿,而肠壁内未发现。22例溃疡性结肠炎肠系膜淋巴结大小与克罗恩病无明显差异。组织学切片上的淋巴结直径被证明低估了新鲜状态下淋巴结直径的1·5倍。
The size of the related lymph nodes and their histology has been correlated in 34 specimens of Crohn's disease. Granulomata were shown not to affect the maximum diameter of the lymph nodes nor to be more frequent in large nodes. The enlargement of lymph nodes appeared to be due to simple, non-specific, reactive changes. Granulomatous lymph nodes were found in 38% of all our cases of Crohn's disease and in 63% of those cases with granulomata in the bowel wall. One case was found with granulomata in the lymph nodes which were not seen in the bowel wall. The mesenteric lymph nodes of 22 cases of ulcerative colitis were shown to be not significantly different in size from those of Crohn's disease. The diameter of the lymph nodes on the histological section was shown to underestimate the diameter of nodes in the fresh state by a factor of 1·5.