Cross-Species GacA-Controlled Induction of Antibiosis in Pseudomonads
Cross-Species GacA-Controlled Induction of Antibiosis in Pseudomonads
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DOI：
10.1128/aem.01681-06
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发表时间：
2006-11
影响因子：
4.4
通讯作者：
C. Dubuis;D. Haas
中科院分区：
文献类型：
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作者：
C. Dubuis;D. Haas
从荧光假单胞菌CHA 0和铜绿假单胞菌PAO的培养上清液中制备的信号提取物刺激两种宿主中小RNA的GacA依赖性表达，从而刺激抗生素化合物的表达。波纹假单胞菌LMG 2172和荧光假单胞菌SBW 25也产生刺激菌株CHA 0中GacA控制的抗生素合成的信号分子，说明了一种新的，N-酰基高丝氨酸内酯独立型的种间通讯。
ABSTRACT Signal extracts prepared from culture supernatants of Pseudomonas fluorescens CHA0 and Pseudomonas aeruginosa PAO stimulated GacA-dependent expression of small RNAs and hence of antibiotic compounds in both hosts. Pseudomonas corrugata LMG2172 and P. fluorescens SBW25 also produced signal molecules stimulating GacA-controlled antibiotic synthesis in strain CHA0, illustrating a novel, N-acyl-homoserine lactone-independent type of interspecies communication.