The control of clonorchiasis in Guangdong province, southern China
The control of clonorchiasis in Guangdong province, southern China
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DOI：
10.1016/j.actatropica.2019.105246
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发表时间：
2020-02-01
期刊：
影响因子：
2.7
通讯作者：
Liu, Meng-Ran
中科院分区：
文献类型：
--
作者：
Deng, Zhuo-Hui;Fang, Yue-Yi;Liu, Meng-Ran
东方肝吸虫病是由华支睾吸虫引起的广东省81个县的地方性流行病。这项研究是在越来越缺乏华支睾吸虫病的认识和增加消费的生淡水鱼和生鱼粥在家庭和餐馆，这已被归因于提高生活水平在中国，并被认为是导致较高的C。中国的感染率。1988年省级调查期间，共调查了123个地点的61，517人，平均C。中华按蚊感染率1.82%，1997年上升到4.08%（335/8217）。成年男子的感染率高于妇女，渔民和商人的感染率很高，因为他们有机会和手段获得生鱼供消费。华支睾吸虫病已成为广东省严重的公共卫生问题。广东省华支睾吸虫病防治工作始于20世纪90年代。其中包括在流行地区进行大规模调查和化疗，研究促进环境卫生和淡水水产养殖方法。开始建立和推广华支睾吸虫病综合防治措施示范区，以及发展华支睾吸虫病预防社区门诊，并对其效果进行了评价。然而，C的患病率似乎没有明显下降。2015年广东省中华按蚊感染率为4.90%（608/12，401），主要是由于流行区居民食用生食鱼类的习惯所致。这导致越来越多的人呼吁改善水产养殖业的环境卫生。然而，据认为，该省对华支睾吸虫病的控制工作仍处于早期阶段，需要通过不同部门的合作来加强，以制定有效的战略，可持续地实地应用控制机制。
Oriental liver fluke disease (clonorchiasis), caused by Clonorchis sinensis, is endemic in 81 counties in Guangdong province, China. This study was conducted following increasing lack of clonorchiasis awareness and increased consumption of raw freshwater fish and raw fish porridge at home and restaurants, which has been attributed to improved living standards in China, and is considered to have led to a higher C. sinensis infection rate in the country. A total of 61,517 individuals were investigated from 123 sites during a provincial survey in 1988, with average C. sinensis infection rate of 1.82% that increased to 4.08% (335/8217) in 1997. Higher infection rate was observed in adult men than women, with heavy infection rate in fishermen and businessmen because they have access and means to get raw fishes for consumption. Thus, clonorchiasis has become a serious public health problem in Guangdong province. Efforts targeting clonorchiasis prevention and control in Guangdong province started in the 1990s. These included carrying out large-scale surveys and chemotherapy in epidemic regions, research on promotion of environmental sanitation and methods for freshwater aquaculture. Establishment and promotion of clonorchiosis demonstration plots for comprehensive control measures, as well as the development of clonorchiasis-prevention community-out-patient clinics were initiated and their effectiveness was evaluated. However, there seem to be no obvious decline in the prevalence of C. sinensis with 4.90% (608/12,401) in 2015, at Guangdong province due to the people's habit of eating raw fishes in endemic areas. This has led to increasing calls to improve environmental sanitation in the aquaculture industry. It is, however, believed that control efforts on clonorchiosis in the province are at an early stage and require strengthening through the cooperation of different departments to work out effective strategies for sustainable field application of control mechanisms.