Recurrence of pemphigus vulgaris associated with interleukin 2 therapy.
Recurrence of pemphigus vulgaris associated with interleukin 2 therapy.
复制标题
寻常型天疱疮的复发与白细胞介素 2 治疗相关。
DOI：
10.1001/archderm.1994.01690070084013
复制
发表时间：
1994
影响因子：
--
通讯作者：
J. Stanley
中科院分区：
文献类型：
--
作者：
R. Prussick;R. T. Plott;J. Stanley
背景
重组白细胞介素2的免疫治疗可能导致转移性癌症的消退，特别是恶性黑色素瘤和肾细胞癌。
意见
我们描述了一个病人谁接受白细胞介素2免疫治疗转移性肾细胞癌。在他的第二个疗程后，他患上了复发的寻常天疱疮，已经缓解了10年。
结论
白细胞介素2治疗可能与自身免疫性疾病的复发有关，这可能是因为其刺激自身抗体产生的能力。
BACKGROUND
Immunotherapy with recombinant interleukin 2 may result in regression of metastatic cancer, particularly malignant melanoma and renal cell carcinoma.
OBSERVATIONS
We describe a patient who received interleukin 2 immunotherapy for metastatic renal cell carcinoma. After his second course of treatment, he developed a recurrence of pemphigus vulgaris that had been in remission for 10 years.
CONCLUSIONS
Interleukin 2 therapy may be associated with recurrence of an autoimmune disease, perhaps because of its ability to stimulate autoantibody production.