Hadamard amino-acid-type edited NMR experiment for fast protein resonance assignment
Hadamard amino-acid-type edited NMR experiment for fast protein resonance assignment
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DOI：
10.1021/ja800914h
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发表时间：
2008-04-16
影响因子：
15
通讯作者：
Brutscher, Bernhard
中科院分区：
文献类型：
--
作者：
Lescop, Ewen;Rasia, Rodolfo;Brutscher, Bernhard
原始的Hadamard编码方案允许在单个二维核磁共振实验中区分七种氨基酸类型。与超维核磁共振技术相结合，这是一种很有前途的新方法，可以在几个小时内快速、自动地指定蛋白质的主干共振。
An original Hadamard-encoding scheme allows discrimination among seven amino acid types in a single two-dimensional NMR experiment. Combined with hyperdimensional NMR techniques, this presents a promising new, method for fast, automated backbone resonance assignment of proteins in only a few hours time.