Organization of sensory neocortex in prairie voles (Microtus ochrogaster)
Organization of sensory neocortex in prairie voles (Microtus ochrogaster)
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DOI：
10.1002/cne.21314
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发表时间：
2007-05-20
影响因子：
2.5
通讯作者：
Krubitzer, Leah
中科院分区：
文献类型：
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作者：
Campi, Katharine L.;Karlen, Sarah J.;Krubitzer, Leah
在目前的调查中，视觉，听觉和躯体感觉皮层的功能组织在草原田鼠（Microtus ochrogaster）的研究，通过使用电生理记录技术。皮质区的功能边界与骨髓结构边界直接相关。我们的研究结果表明，大部分的新皮层是由视觉，听觉和躯体感觉区。具体来说，一个小区域17，或主要视觉区（VI），位于新皮层的尾内侧极;一个大的听觉皮层（AC），包含主要听觉区（A1）和其他听觉领域，几乎涵盖了整个颞极;和一个大区域3b，或主要躯体感觉区（S1），包含对侧体表的完整代表。此外，这些区域同延，具有不同的骨髓结构外观。我们还观察到，AC似乎是不成比例的大草原田鼠与其他啮齿动物相比。此外，我们还发现，初级和非初级区域都含有对听觉刺激做出反应的神经元。最后，我们在S1中观察到，用于代表口周毛和口鼻部的皮层的数量不成比例，并且该代表中的神经元具有非常小的感受野。我们讨论了扩大的听觉域和口周毛的扩大表示，因为它们涉及到专门的生活方式的草原田鼠。
In the current investigation, the functional organization of visual, auditory, and somatosensory cortex was examined in prairie voles (Microtus ochrogaster) by using electrophysiological recording techniques. Functional boundaries of cortical fields were directly related to myeloarchitectonic boundaries. Our results demonstrated that most of the neocortex is occupied by the visual, auditory, and somatosensory areas. Specifically, a small area 17, or primary visual area (VI), was located on the caudomedial pole of the neocortex; a large auditory cortex (AC), which contains the primary auditory area (A1) and other auditory fields, encompassed almost the entire temporal pole; and a large area 3b, or primary somatosensory area (S1), contained a complete representation of the contralateral body surface. Furthermore, these areas were coextensive with distinct myeloarchitectonic appearances. We also observed that the AC appeared to be disproportionately large in the prairie vole compared with other rodents. In addition, we found that both primary and nonprimary areas contained neurons that responded to auditory stimulation. Finally, we observed within S1 a disproportionate amount of cortex that was devoted to representing the perioral hairs and the snout and also that neurons within this representation had very small receptive fields. We discuss the expanded auditory domain and the enlarged representation of perioral hairs as they relate to the specialized life style of the prairie vole.