Endoscopic resection for submucosally invasive colorectal cancer - Is it feasible?
Endoscopic resection for submucosally invasive colorectal cancer - Is it feasible?
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DOI：
10.1007/s004649900949
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发表时间：
1999-03-01
期刊：
影响因子：
--
通讯作者：
Kawano, N
中科院分区：
文献类型：
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作者：
Kawamura, YJ;Sugamata, Y;Kawano, N
背景：结肠镜检查的最新进展导致越来越多的结肠直肠肿瘤内镜切除术。然而，内镜下黏膜下浸润性癌切除术仍然是一个有争议的issues.Methods：本研究的主题是手术治疗的患者与黏膜下浸润性结直肠癌，这些患者分为两组：那些与那些没有术前内镜下切除术。结果：50例粘膜下浸润性结直肠癌均行手术治疗。术前内镜下切除和未切除的患者数量分别为22例和28例。36.4%的患者内镜下切除不完全。两名患者术前内镜切除术显示癌边缘阳性，有淋巴结转移。其中1例患者还发生了肝转移。内窥镜检查结果，如直径和形状并不表明淋巴或血管浸润。没有与内窥镜切除或手术相关的发病率或死亡率。结论：只要切除完整，结直肠粘膜下癌的术前内窥镜切除是可行的。手术治疗的指征应在病理检查后确定。
Background: Recent advances in colonoscopy have resulted in an increasing number of endoscopic resections of colorectal neoplasms. However, endoscopic resection of submucosal invasive cancer remains a controversial issue.Methods: The subjects for this study were the surgically treated patients with submucosal invasive colorectal cancer; These patients were classified into two groups: those with versus those without preoperative endoscopic resection. Clinicopathologic features and prognosis were compared and analyzed.Results: Fifty patients underwent surgery for submucosally invasive colorectal cancer. Numbers of patients with and without preoperative endoscopic resection were 22 and 28, respectively. in 36.4% of the patients, endoscopic resections were incomplete. Two patients in whom the preoperative endoscopic resections had revealed a positive cancer margin, had nodal metastasis. One of these patients also developed hepatic metastasis. Endoscopic findings such as diameter and shape were not indicative of either lymphatic or vascular invasion. There were no morbidities or mortalities associated with endoscopic resection or surgery.Conclusions: Preoperative endoscopic resection for colorectal submucosal cancer is feasible, provided the resection is complete. The indications for surgical treatment should be determined after pathologic examination.