Behavioral adjustment moderates the effect of neuroticism on brain volume relative to intracranial volume
Behavioral adjustment moderates the effect of neuroticism on brain volume relative to intracranial volume
复制标题
行为调整调节神经质对脑容量相对于颅内容积的影响
DOI：
10.1111/jopy.12858
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发表时间：
2023
影响因子：
5
通讯作者：
Kitayama, Shinobu
中科院分区：
文献类型：
--
作者：
Yu, Qinggang;Schaefer, Stacey M.;Davidson, Richard J.;Kitayama, Shinobu
本研究旨在探讨神经质对大脑结构的影响是否受到行为调整的调节。然而，最近使用促炎生物标志物的工作表明，这种影响取决于行为调整，调整和科普环境突发事件的意愿和能力，例如他人的不同意见或不可预测的生活情况。在这里，我们试图将这一观察扩展到“大脑健康”的测试总脑容量（TBV）。MethodUsing一个社区样本的125名美国人，我们研究了结构磁共振成像的大脑和量化TBV。我们测试了是否神经质TBV的影响是缓和的行为调整，净颅内容量，年龄，性别，教育成就，和race.ResultsBehavioral调整显着缓和的神经质TBV的影响，这样的神经质与较低的TBV只有当行为调整低。有没有这样的效果时，行为调整high.ConclusionThe目前的研究结果表明，神经质是不是削弱那些建设性地科普压力。影响进行了进一步讨论。
ObjectiveThe present study examined whether the effect of neuroticism on brain structure is moderated by behavioral adjustment.BackgroundNeuroticism is widely thought to be harmful to health. However, recent work using proinflammatory biomarkers showed that this effect depends on behavioral adjustment, the willingness and ability to adjust and cope with environmental contingencies, such as different opinions of others or unpredictable life situations. Here, we sought to extend this observation to “brain health” by testing total brain volume (TBV).MethodUsing a community sample of 125 Americans, we examined structural magnetic resonance imaging of the brain and quantified TBV. We tested whether the effect of neuroticism on TBV was moderated by behavioral adjustment, net of intracranial volume, age, sex, educational achievement, and race.ResultsBehavioral adjustment significantly moderated the effect of neuroticism on TBV, such that neuroticism was associated with lower TBV only when behavioral adjustment was low. There was no such effect when behavioral adjustment was high.ConclusionThe present findings suggest that neuroticism is not debilitating to those who constructively cope with stress. Implications are further discussed.