Dose-response association of screen time-based sedentary behaviour in children and adolescents and depression: a meta-analysis of observational studies.
Dose-response association of screen time-based sedentary behaviour in children and adolescents and depression: a meta-analysis of observational studies.
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DOI：
10.1136/bjsports-2015-095084
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发表时间：
2016-10
影响因子：
18.4
通讯作者：
Yao S
中科院分区：
文献类型：
--
作者：
Liu M;Wu L;Yao S
抑郁症是一个日益严重的公共卫生负担。了解青少年的屏幕时间（ST）如何与抑郁症的风险相关，对于制定预防和干预策略至关重要。迄今为止，针对这一问题的研究结果并不一致。因此，我们对与该问题相关的数据进行了全面的系统回顾和荟萃分析。根据PRISMA指南进行荟萃分析。我们系统地检索了PubMed、Web of Science和EBSCO的电子数据库（截至2015年5月6日）。采用OR作为ST和抑郁风险之间关联的汇总测量。通过广义最小二乘趋势估计法估计剂量反应。纳入了12项横断面研究和4项纵向研究（包括1项队列研究），共涉及127 714例受试者。总体而言，青春期前儿童和青少年的ST较高与抑郁症的风险较高显著相关（OR=1.12; 95%CI 1.03至1.22）。屏幕类型，年龄，人口和参考类别作为显着的主持人。与没有ST的参考组相比，ST<2 h/d时，ST与抑郁风险降低呈非线性剂量-反应关系，1 h/d时观察到的风险最低（OR=0.88; 95%CI 0.84 - 0.93）。 我们的荟萃分析表明，ST在儿童和青少年与抑郁症的风险在一个非线性的剂量反应方式。
Depression represents a growing public health burden. Understanding how screen time (ST) in juveniles may be associated with risk of depression is critical for the development of prevention and intervention strategies. Findings from studies addressing this question thus far have been inconsistent. Therefore, we conducted a comprehensive systematic review and meta-analysis of data related to this question. The meta-analysis was conducted in accordance with the PRISMA guideline. We searched the electronic databases of PubMed, Web of Science and EBSCO systematically (up to 6 May 2015). OR was adopted as the pooled measurement of association between ST and depression risk. Dose–response was estimated by a generalised least squares trend estimation. Twelve cross-sectional studies and four longitudinal studies (including 1 cohort study) involving a total of 127 714 participants were included. Overall, higher ST in preadolescent children and adolescents was significantly associated with a higher risk of depression (OR=1.12; 95% CI 1.03 to 1.22). Screen type, age, population and reference category acted as significant moderators. Compared with the reference group who had no ST, there was a non-linear dose–response association of ST with a decreasing risk of depression at ST<2 h/day, with the lowest risk being observed for 1 h/day (OR=0.88; 95% CI 0.84 to 0.93). Our meta-analysis suggests that ST in children and adolescents is associated with depression risk in a non-linear dose–response manner.