Antimicrobial triterpenes from Debregeasia salicifolia
Antimicrobial triterpenes from Debregeasia salicifolia
复制标题
DOI：
10.1080/10575630290033088
复制
发表时间：
2002-10-01
期刊：
影响因子：
--
通讯作者：
Malik, A
中科院分区：
文献类型：
--
作者：
Akbar, E;Malik, A
从水麻（Debregeasia salicifolia）的甲醇提取物中分离得到一个新的三萜化合物，3 β-（trans-cinnamoyloxy）-19 α-hydroxy-urs-12-ene（1），另外沿着3 β，19 α-dihydroxy-urs-12-ene（2），3 β，19 α-dihydroxy-urs-12-ene（3），ursolic acid（4），pomolic acid（5），pomolic acid methyl ester（6）和tormentic acid（7）为首次报道。化合物（1）、（3）和（6）显示出明显的抑菌活性。借助广泛的2D NMR光谱技术进行了结构鉴定。
New triterpene, 3beta-(trans-cinnamoyloxy)-19alpha-hydroxy-urs-12-ene (1) has been isolated from the methanolic fraction of Debregeasia salicifolia, along with uvaol (2), 3beta,19alpha-dihydroxy-urs-12-ene (3), ursolic acid (4), pomolic acid (5), pomolic acid methyl ester (6) and tormentic acid (7) reported for the first time from this species. The compounds (1), (3) and (6) showed significant antimicrobial activity. The structure elucidation was made with the help of extensive 2D NMR spectroscopic techniques.