Health-related quality of life in longterm survivors after treatment with extracorporeal membrane oxygenation (ECMO) for the acute respiratory distress syndrome (ARDS)
Health-related quality of life in longterm survivors after treatment with extracorporeal membrane oxygenation (ECMO) for the acute respiratory distress syndrome (ARDS)
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DOI：
10.1007/s001010050518
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发表时间：
1998-01-01
期刊：
影响因子：
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通讯作者：
Schelling, G
中科院分区：
文献类型：
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作者：
Stoll, C;Haller, M;Schelling, G
使用体外膜氧合（ECMO）治疗严重急性呼吸窘迫综合征（ARDS）可以挽救生命，但需要长时间最大限度地使用重症监护资源，导致高昂的费用。对于长期幸存者的健康相关生活质量（HRQL）知之甚少。本病例对照回顾性研究旨在评估ARDS和ecmo治疗的长期幸存者的健康相关生活质量。方法：选取1992 - 1995年间（数据收集至出院的中位时间间隔为16个月）采用ECMO治疗的ARDS长期存活患者14例（APACHE II评分=24，肺损伤评分=3.25，中位数）和同期常规治疗的ARDS患者14例（I组），并填写SF-36健康状况问卷（Medical Outcome Trust, Boston， USA）。从提供德国人群SF-36正常值的大型数据库中随机抽取14名健康受试者（II组）。这三组在性别和年龄方面具有可比性。结果：与单独机械通气治疗的患者相比，ecmo治疗的长期幸存者报告了身体功能的显著降低(I组，-12.5%,p
Treatment of severe acute respiratory distress syndrome (ARDS) with extracorporeal membrane oxygenation (ECMO) can be lifesaving but requires maximal use of intensive care resources over prolonged periods of time, resulting in high costs. Little is known about the health-related quality of life (HRQL) in long-term survivors. This case-controlled retrospective study was designed to assess the health-related quality of life in long-term survivors of ARDS and ECMO-therapy.Methods: 14 long-term survivors of ARDS (APACHE II score=24, Lung Injury Score=3.25, median values) treated using ECMO between 1992 and 1995 (median time interval between data collection and discharge from the ICU 16 months) and 14 ARDS-patients conventionally treated during the same period (group I) were identified and completed the SF-36 Health Status Questionnaire (Medical Outcome Trust, Boston, USA). 14 healthy subjects (group II) were drawn at random from a large data base generated to provide normal values for the SF-36 in a German population. All three groups were comparable with respect to sex and age.Results: Long-term survivors of ECMO-therapy reported significant reductions in physical functioning when compared with patients treated by mechanical ventilation alone (group I, -12.5%, p