Neuronal activity in the claustrum of the monkey during performance of multiple movements.
Neuronal activity in the claustrum of the monkey during performance of multiple movements.
复制标题
进行多次运动时猴子屏状体中的神经元活动。
DOI：
10.1152/jn.1996.76.3.2115
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发表时间：
1996
影响因子：
2.5
通讯作者：
Jun Tanji
中科院分区：
文献类型：
--
作者：
K. Shima;E. Hoshi;Jun Tanji
1. 我们研究了猴子进行三种不同手臂动作时屏状体中的神经元活动。我们通过微损伤的组织学确认来验证幽闭神经元的记录位点。为了进行比较，我们还记录了手臂区域的中央前运动皮层（MI）。动作的选择要么是视觉引导的，要么是由记忆的信息确定的。 2. 幽闭神经元的一个显着特性是它们与三种运动（推、拉和转动操作器）的非选择性关系。绝大多数 (70%) 运动相关神经元在所有三种运动中表现出放电增加，而只有 16% 的神经元在三种运动中的一种中表现出活跃。相比之下，心肌梗塞中大约有一半的神经元在一次运动中是活跃的。在这两个区域中，无论运动是通过视觉信号还是通过记忆选择，与运动相关的活动都是相似的。 3. 该研究首次揭示了幽闭神经元参与运动执行，其活动特性表明其参与方式与 MI 神经元不同。
1. We studied neuronal activity in the claustrum of monkeys during performance of three different arm movements. We verified recording sites of claustral neurons by histological confirmation of microlesions. For the sake of comparison, we also recorded from the arm area of the precentral motor cortex (MI). Selection of the movements was either visually guided or determined by memorized information. 2. A striking property of claustral neurons is their nonselective relation to the three movements (push, pull, and turn a manipulandum). A vast majority (70%) of movement-related neurons exhibited increase of discharge in relation to all three movements, whereas only 16% were active in relation to one of the three movements. By contrast, about one-half of neurons in the MI were active in relation to a single movement. In both areas, the movement-related activity was similar regardless of whether the movements were selected by visual signals or by memory. 3. The study is the first to reveal involvement of claustral neurons in motor execution, and their activity property suggests that the way they are involved is different from that of MI neurons.